Renal neoplasms in a family

British Journal of Radiology - Tập 62 Số 733 - Trang 83-84 - 1989
Valérie Laurence1, Anthony C. Robinson1
1Cookridge Hospital, Leeds

Tóm tắt

Malignant tumours of the kidney are uncommon, renal cell carcinoma, the adult variety, accounting for 2% of all adult malignancies, whilst nephroblastoma, an enbryonic tumour of childhood, affects one per 200 000 children per year under the age of 15 years and constitutes 7% of childhood neoplasms (Bullimore & Mott, 1982). Both of these tumours occur in sporadic and hereditary forms. We report a family in which the mother had renal cell carcinoma and her son nephroblastoma. This has only been reported once before (Campbell et al, 1987). In January 1975, a previously healthy 4-year-old boy presented with right-sided abdominal swelling. He had one healthy brother aged 9 months. Family history was otherwise unremarkable. Physical examination revealed a large abdominal mass. No other abnormalities were detected.

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