Regional cerebral blood flow after recovery from anorexia or bulimia nervosa

International Journal of Eating Disorders - Tập 40 Số 6 - Trang 488-492 - 2007
Guido Frank1,2, Ursula F. Bailer3,2, Carolyn C. Meltzer2,4, Julie C. Price5, Chester A. Mathis5, Angela Wagner6, Carl Becker5, Walter H. Kaye2
1Department of Child and Adolescent Psychiatry, San Diego School of Medicine, University of California, San Diego, California
2Department of Psychiatry, Western Psychiatric Institute and Clinic, University of Pittsburgh, School of Medicine, Pittsburgh, Pennsylvania
3Department of Biological Psychiatry, University Hospital of Psychiatry and Psychotherapy, Medical University of Vienna, Vienna, Austria
4Department of Radiology, Emory University Hospital, Atlanta, Georgia
5Department of Radiology, Presbyterian University Hospital, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania
6Department of child and Adolescent Psychiatry and Psychotherapy, J. W. Goethe University, Frankfurt, Germany

Tóm tắt

AbstractObjective:

Abnormalities of regional cerebral blood flow (rCBF) have been found in individuals who are ill with anorexia (AN) or bulimia nervosa (BN). Little is known about whether rCBF normalizes after recovery from AN and BN.

Method:

Eighteen control women (CW), 10 recovered restricting type AN, 8 recovered AN with a binging history, and 9 recovered BN participants without a history of AN were studied using positron emission tomography and [15O]water in order to assess rCBF.

Results:

Partial volume corrected rCBF values in cortical and subcortical brain regions were similar between groups. Neither current body mass index nor age correlated with rCBF values.

Conclusion:

The results from this study indicate that rCBF normalizes with long‐term recovery. Thus, altered rCBF is unlikely to confound functional imaging studies in AN or BN after recovery. © 2007 by Wiley Periodicals, Inc. Int J Eat Disord 2007.

Từ khóa


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Thông tin
Thông tin xuất bản

International Journal of Eating Disorders

Tập 40 Số 6

488-492

Thông tin tác giả