Reduction of eddy‐current‐induced distortion in diffusion MRI using a twice‐refocused spin echo

Magnetic Resonance in Medicine - Tập 49 Số 1 - Trang 177-182 - 2003
Timothy G. Reese1, O. Heid2, Robert M. Weisskoff3, Van J. Wedeen4
1Department of Radiology, Massachusetts General Hospital, Boston, Massachusetts USA
2Medical Engineering Division, Siemens AG, Erlangen, Germany
3Epix Medical Inc., Cambridge, Massachusetts
4Department of Radiology, Massachusetts General Hospital, Boston, Massachusetts

Tóm tắt

AbstractImage distortion due to field gradient eddy currents can create image artifacts in diffusion‐weighted MR images. These images, acquired by measuring the attenuation of NMR signal due to directionally dependent diffusion, have recently been shown to be useful in the diagnosis and assessment of acute stroke and in mapping of tissue structure. This work presents an improvement on the spin‐echo (SE) diffusion sequence that displays less distortion and consequently improves image quality. Adding a second refocusing pulse provides better image quality with less distortion at no cost in scanning efficiency or effectiveness, and allows more flexible diffusion gradient timing. By adjusting the timing of the diffusion gradients, eddy currents with a single exponential decay constant can be nulled, and eddy currents with similar decay constants can be greatly reduced. This new sequence is demonstrated in phantom measurements and in diffusion anisotropy images of normal human brain. Magn Reson Med 49:177–182, 2003. © 2003 Wiley‐Liss, Inc.

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Thông tin xuất bản

Magnetic Resonance in Medicine

Tập 49 Số 1

177-182

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