Akiyama, 2013, Neural processing of itch, Neuroscience, 250, 697, 10.1016/j.neuroscience.2013.07.035
Akiyama, 2014, Chapter 19: Spinal coding of itch and pain
Akiyama, 2011, Transmitters and pathways mediating inhibition of spinal itch-signaling neurons by scratching and other counterstimuli, PLoS One, 6, e22665, 10.1371/journal.pone.0022665
Alvarez-Dolado, 2006, Cortical inhibition modified by embryonic neural precursors grafted into the postnatal brain, J. Neurosci., 26, 7380, 10.1523/JNEUROSCI.1540-06.2006
Baraban, 2009, Reduction of seizures by transplantation of cortical GABAergic interneuron precursors into Kv1.1 mutant mice, Proc. Natl. Acad. Sci., 106, 15472, 10.1073/pnas.0900141106
Basbaum, 2016, Cell transplants to treat the “disease” of neuropathic pain and itch, Pain, 157, S42, 10.1097/j.pain.0000000000000441
Basbaum, 2009, Cellular and molecular mechanisms of pain, Cell, 139, 267, 10.1016/j.cell.2009.09.028
Ben Smail, 2005, Pruritus after intrathecal baclofen withdrawal: a retrospective study, Arch. Phys. Med. Rehabil., 86, 494, 10.1016/j.apmr.2004.09.001
Bráz, 2002, Transneuronal tracing of diverse CNS circuits by Cre-mediated induction of wheat germ agglutinin in transgenic mice, Proc. Natl. Acad. Sci. U.S.A., 99, 15148, 10.1073/pnas.222546999
Bráz, 2012, Forebrain GABAergic neuron precursors integrate into adult spinal cord and reduce injury-induced neuropathic pain, Neuron, 74, 663, 10.1016/j.neuron.2012.02.033
Bráz, 2014, Transplant restoration of spinal cord inhibitory controls ameliorates neuropathic itch, J. Clin. Invest., 124, 3612, 10.1172/JCI75214
Bráz, 2014, Transmitting pain and itch messages: a contemporary view of the spinal cord circuits that generate gate control, Neuron, 82, 522, 10.1016/j.neuron.2014.01.018
Bráz, 2014
Bráz, 2015, Transplant-mediated enhancement of spinal cord GABAergic inhibition reverses paclitaxel-induced mechanical and heat hypersensitivity, Pain, 156, 1084, 10.1097/j.pain.0000000000000152
Bráz, 2016
Budenkotte, 2010, Histamine and antihistamines in atopic dermatitis, Adv. Exp. Med. Biol, 709, 73, 10.1007/978-1-4419-8056-4_8
Calcagnotto, 2010, Grafting of GABAergic precursors rescues deficits in hippocampal inhibition, Epilepsia, 51, 66, 10.1111/j.1528-1167.2010.02613.x
Castro-Lopes, 1993, GABA decreases in the spinal cord dorsal horn after peripheral neurectomy, Brain Res., 620, 287, 10.1016/0006-8993(93)90167-L
Cevikbas, 2011, Role of spinal neurotransmitter receptors in itch: new insights into therapies and drug development, CNS Neurosci. Ther., 17, 742, 10.1111/j.1755-5949.2010.00201.x
Cevikbas, 2014, A sensory neuron-expressed IL-31 receptor mediates T helper cell-dependent itch: involvement of TRPV1 and TRPA1, J. Allergy Clin. Immunol., 133, 448, 10.1016/j.jaci.2013.10.048
Chambers, 2009, Highly efficient neural conversion of human ES and iPS cells by dual inhibition of SMAD signaling, Nat. Biotechnol., 27, 275, 10.1038/nbt.1529
Chiang, 2016, Insight into B5-I spinal interneurons and their role in the inhibition of itch and pain, Pain, 157, 544, 10.1097/j.pain.0000000000000474
De Koninck, 2007, Altered chloride homeostasis in neurological disorders: a new target, Curr. Opin. Pharmacol., 7, 93, 10.1016/j.coph.2006.11.005
Eaton, 1998, Changes in GAD- and GABA- immunoreactivity in the spinal dorsal horn after peripheral nerve injury and promotion of recovery by lumbar transplant of immortalized serotonergic precursors, J. Chem. Neuroanat., 16, 57, 10.1016/S0891-0618(98)00062-3
Eaton, 1999, Transplants of neuronal cells bioengineered to synthesize GABA alleviate chronic neuropathic pain, Cell Transplant., 8, 87, 10.1177/096368979900800102
Etlin A., Braz J.M., Kuhn J.A., Wang X., Hamel K., Llewellyn-Smith I.J. Basbaum A.I., 2016. Functional synaptic integration of forebrain GABAergic precursors into the adult spinal cord, J. Neurosci. (in press).
Flatters, 2006, Studies of peripheral sensory nerves in paclitaxel-induced painful peripheral neuropathy: evidence for mitochondrial dysfunction, Pain, 122, 245, 10.1016/j.pain.2006.01.037
Fromm, 1984, Baclofen in the treatment of trigeminal neuralgia: double-blind study and long-term follow-up, Ann. Neurol., 15, 240, 10.1002/ana.410150306
Fukuoka, 1998, Change in mRNAs for neuropeptides and the GABA(A) receptor in dorsal root ganglion neurons in a rat experimental neuropathic pain model, Pain, 78, 13, 10.1016/S0304-3959(98)00111-0
Gilron, 2015, Neuropathic pain: principles of diagnosis and treatment, Mayo Clin. Proc., 90, 532, 10.1016/j.mayocp.2015.01.018
Han, 2013, A subpopulation of nociceptors specifically linked to itch, Nat. Neurosci., 16, 174, 10.1038/nn.3289
Hentall, 2000, The alleviation of pain by cell transplantation, Prog. Brain Res., 127, 535, 10.1016/S0079-6123(00)27027-1
Hwang, 1997, The effect of spinal GABA receptor agonists on tactile allodynia in a surgically-induced neuropathic pain model in the rat, Pain, 70, 15, 10.1016/S0304-3959(96)03249-6
Ibuki, 1997, Loss of GABA-immunoreactivity in the spinal dorsal horn of rats with peripheral nerve injury and promotion of recovery by adrenal medullary grafts, Neuroscience, 76, 845, 10.1016/S0306-4522(96)00341-7
Imamachi, 2009, TRPV1-expressing primary afferents generate behavioral responses to pruritogens via multiple mechanisms, Proc. Natl. Acad. Sci., 106, 11330, 10.1073/pnas.0905605106
Jain, 2003, GABAergic immunoreactivity is predominant in neurons derived from expanded human neural precursor cells in vitro, Exp. Neurol., 182, 113, 10.1016/S0014-4886(03)00055-4
Jasmin, 1997, Transneuronal labeling of a nociceptive pathway, the spino-(trigemino-)parabrachio-amygdaloid, in the rat, J. Neurosci., 17, 3751, 10.1523/JNEUROSCI.17-10-03751.1997
Julius, 2001, Molecular mechanisms of nociception, Nature, 413, 203, 10.1038/35093019
Kaneko, 1997, Role of spinal gamma-aminobutyric acidA receptors in formalin-induced nociception in the rat, J. Pharmacol. Exp. Ther., 282, 928
Kardon, 2014, Dynorphin acts as a neuromodulator to inhibit itch in the dorsal horn of the spinal cord, Neuron, 82, 573, 10.1016/j.neuron.2014.02.046
Kim, 2011, Analysis of cellular and behavioral responses to imiquimod reveals a unique itch pathway in transient receptor potential vanilloid 1 (TRPV1)-expressing neurons, Proc. Natl. Acad. Sci. U.S.A., 108, 3371, 10.1073/pnas.1019755108
Kim, 2016, Molecular mechanisms of cutaneous inflammatory disorder: atopic dermatitis, Int. J. Mol. Sci., 17, E1234, 10.3390/ijms17081234
Knabl, 2008, Reversal of pathological pain through specific spinal GABAA receptor subtypes, Nature, 451, 330, 10.1038/nature06493
Kohno, 2003, Peripheral nerve injury alters excitatory synaptic transmission in lamina II of the rat dorsal horn, J. Physiol., 548, 131, 10.1113/jphysiol.2002.036186
Laing, 1994, Subpopulations of GABAergic neurons in laminae I-III of rat spinal dorsal horn defined by coexistence with classical transmitters, peptides, nitric oxide synthase or parvalbumin, Neuroscience, 61, 123, 10.1016/0306-4522(94)90065-5
LaMotte, 2014, Sensory neurons and circuits mediating itch, Nat. Rev. Neurosci., 15, 19, 10.1038/nrn3641
Lipton, 1989, Taxol produces a predominantly sensory neuropathy, Neurology, 39, 368, 10.1212/WNL.39.3.368
Liu, 2013, New insights into the mechanisms of itch: are pain and itch controlled by distinct mechanisms?, Pflugers Arch., 465, 1671, 10.1007/s00424-013-1284-2
Liu, 2009, Sensory neuron-specific GPCR Mrgprs are itch receptors mediating chloroquine-induced pruritus, Cell, 139, 1353, 10.1016/j.cell.2009.11.034
Liu, 2011, Unidirectional cross-activation of GRPR by MOR1D uncouples itch and analgesia induced by opioids, Cell, 147, 447, 10.1016/j.cell.2011.08.043
Malan, 2002, GABA(A) and GABA(B) receptor pharmacology in a rat model of neuropathic pain, Anesthesiology, 96, 1161, 10.1097/00000542-200205000-00020
Maricich, 1999, Pax-2 expression defines a subset of GABAergic interneurons and their precursors in the developing murine cerebellum, J. Neurobiol., 41, 281, 10.1002/(SICI)1097-4695(19991105)41:2<281::AID-NEU10>3.0.CO;2-5
Marin, 2001, A long, remarkable journey: tangential migration in the telencephalon, Nat. Rev. Neurosci., 2, 780, 10.1038/35097509
Michalewicz, 1999, Purification of adrenal chromaffin cells increases antinociceptive efficacy of xenotransplants without immunosuppression, Cell Transplant., 8, 103, 10.1177/096368979900800103
Mishra, 2013, The cells and circuitry for itch responses in mice, Science, 340, 968, 10.1126/science.1233765
Moore, 2002, Partial peripheral nerve injury promotes a selective loss of GABAergic inhibition in the superficial dorsal horn of the spinal cord, J. Neurosci., 22, 6724, 10.1523/JNEUROSCI.22-15-06724.2002
Moser, 2014, Itch elicited by intradermal injection of serotonin, intracisternal injection of morphine, and their synergistic interactions in rats, Neuroscience, 274, 119, 10.1016/j.neuroscience.2014.05.025
Mukhida, 2007, Spinal GABAergic transplants attenuate mechanical allodynia in a rat model of neuropathic pain, Stem Cells, 25, 2874, 10.1634/stemcells.2007-0326
Nicholas, 2013, Functional maturation of hPSC-derived forebrain interneurons requires an extended timeline and mimics human neural development, Cell Stem Cell, 12, 573, 10.1016/j.stem.2013.04.005
Polgár, 2008, Tactile allodynia can occur in the spared nerve injury model in the rat without selective loss of GABA or GABA(A) receptors from synapses in laminae I-II of the ipsilateral spinal dorsal horn, Neuroscience, 156, 193, 10.1016/j.neuroscience.2008.07.009
Proudlock, 1993, Immunocytochemical study of somatostatin, neurotensin, GABA, and glycine in rat spinal dorsal horn, J. Comp. Neurol., 327, 289, 10.1002/cne.903270210
Ross, 2011, Pain and itch: insights into the neural circuits of aversive somatosensation in health and disease, Curr. Opin. Neurobiol., 21, 880, 10.1016/j.conb.2011.10.012
Ross, 2010, Loss of inhibitory interneurons in the dorsal spinal cord and elevated itch in Bhlhb5 mutant mice, Neuron, 65, 886, 10.1016/j.neuron.2010.02.025
Rowan, 1993, Evidence that neuropeptide Y is present in GABAergic neurons in the superficial dorsal horn of the rat spinal cord, Neuroscience, 53, 537, 10.1016/0306-4522(93)90218-5
Sagen, 1990, Adrenal medullary implants in the rat spinal cord reduce nociception in a chronic pain model, Pain, 42, 69, 10.1016/0304-3959(90)91093-X
Sandkuhler, 2007, Understanding LTP in pain pathways, Mol. Pain, 3, 3, 10.1186/1744-8069-3-9
Schmelz, 2015, Itch and pain differences and commonalities, Handb. Exp. Pharmacol., 227, 285, 10.1007/978-3-662-46450-2_14
Scholz, 2005, Blocking caspase activity prevents transsynaptic neuronal apoptosis and the loss of inhibition in lamina II of the dorsal horn after peripheral nerve injury, J. Neurosci., 25, 7317, 10.1523/JNEUROSCI.1526-05.2005
Shields, 2003, Spared nerve injury model of neuropathic pain in the mouse: a behavioral and anatomic analysis, J. Pain, 4, 465, 10.1067/S1526-5900(03)00781-8
Silverberg, 2016, Addressing treatment challenges in atopic dermatitis with novels topical therapies, J. Dermatol. Treat., 11, 1
Smith, 2004, Paclitaxel-induced neuropathic hypersensitivity in mice: responses in 10 inbred mouse strains, Life Sci., 74, 2593, 10.1016/j.lfs.2004.01.002
Spike, 1992, Ultrastructural and immunocytochemical study of lamina II islet cells in rat spinal dorsal horn, J. Comp. Neurol., 323, 359, 10.1002/cne.903230305
Sugimoto, 1990, Transsynaptic degeneration in the superficial dorsal horn after sciatic nerve injury: effects of a chronic constriction injury, transection, and strychnine, Pain, 42, 205, 10.1016/0304-3959(90)91164-E
Sun, 2007, A gastrin-releasing peptide receptor mediates the itch sensation in the spinal cord, Nature, 448, 700, 10.1038/nature06029
Szarvas, 2003, Neuraxial opioid-induced pruritus: a review, J. Clin. Anesth, 15, 234, 10.1016/S0952-8180(02)00501-9
Tamamaki, 2003, Green fluorescent protein expression and colocalization with calretinin, parvalbumin, and somatostatin in the GAD67-GFP knock-in mouse, J. Comp. Neurol., 467, 60, 10.1002/cne.10905
Urban-Ciecko, 2016, Somatostatin-expressing neurons in cortical networks, Nat. Rev. Neurosci., 17, 401, 10.1038/nrn.2016.53
Vaysse, 2011, GABAergic pathway in a rat model of chronic neuropathic pain: modulation after intrathecal transplantation of a human neuronal cell line, Neurosci. Res., 69, 111, 10.1016/j.neures.2010.10.006
Wang, 2013, Excitatory superficial dorsal horn interneurons are functionally heterogeneous and required for the full behavioral expression of pain and itch, Neuron, 78, 312, 10.1016/j.neuron.2013.03.001
Wasserheit, 1996, Phase II trial of paclitaxel and cisplatin in women with advanced breast cancer: an active regimen with limiting neurotoxicity, J. Clin. Oncol., 14, 1993, 10.1200/JCO.1996.14.7.1993
Wichterle, 1999, Young neurons from medial ganglionic eminence disperse in adult and embryonic brain, Nat. Neurosci., 2, 461, 10.1038/8131
Winnie, 1993, Subarachnoid adrenal medullary transplants for terminal cancer pain. A report of preliminary studies, Anesthesiology, 79, 644, 10.1097/00000542-199310000-00004
Woolf, 2000, Neuronal plasticity: increasing the gain in pain, Science, 288, 1765, 10.1126/science.288.5472.1765
Yaksh, 2016, Current and future issues in the development of spinal agents for the management of pain, Curr. Neuropharmacol., 10.2174/1570159X14666160210142547
Yu, 1998, Long-term alleviation of allodynia-like behaviors by intrathecal implantation of bovine chromaffin cells in rats with spinal cord injury, Pain, 74, 115, 10.1016/S0304-3959(97)00204-2
Zeilhofer, 2015, Restoring the spinal pain gate: GABA(A) receptors as targets for novel analgesics, Adv. Pharmacol., 73, 71, 10.1016/bs.apha.2014.11.007