Wan Najmi Wan Daud1, Sarah K. Thompson2, Glyn G. Jamieson2, Peter G. Devitt2, Ian J. Martin3, David I. Watson1
1Department of Surgery, Flinders University, Adelaide, South Australia, Australia
2Discipline of Surgery, University of Adelaide, Adelaide, South Australia, Australia
3Department of Surgery, University of Queensland, Brisbane, Queensland, Australia
Tóm tắt
AbstractBackgroundPrevious trials show good outcomes following anterior and posterior partial versus Nissen fundoplication for gastro‐oesophageal reflux. However, it is unclear which partial fundoplication performs best. This study compared anterior 180° versus posterior 270° fundoplication.MethodsAt three hospitals, patients were randomized to anterior 180° versus posterior 270° partial fundoplication, and clinical outcomes were determined using a structured questionnaire at 3, 6 and 12 months. Heartburn, dysphagia and satisfaction were assessed using 0–10 analoue scales, and adverse outcomes and side effects were determined. Endoscopy, manometry and pH monitoring were performed 6 months after surgery.ResultsForty‐seven patients were randomized to anterior (n = 23) versus posterior (n = 24) fundoplication. Clinical outcomes for 93–98% of patients were available at each follow‐up point. At 12 months, the mean heartburn score was higher following anterior fundoplication (2.7 versus 0.8, P = 0.045), although differences were not significant at earlier follow‐up. Conversely, following posterior fundoplication, patients were less able to belch at 3 (56% versus 16%, P = 0.013) and 6 months (43% versus 9%, P = 0.017). No significant differences were demonstrated for dysphagia. Both groups had high rates of satisfaction with the outcome – 85% versus 86% satisfied at 12 months follow‐up.ConclusionBoth partial fundoplications are effective treatments for gastro‐oesophageal reflux. Posterior partial fundoplication is associated with less reflux symptoms offset by more side effects.
