Quality of life and health status before and after ileal pouch–anal anastomosis for ulcerative colitis

British Journal of Surgery - Tập 99 Số 2 - Trang 263-269 - 2012
Joost T. Heikens1,2, Jakob de Vries3,4, Manfred Goos3, H.J.M. Oostvogel2, Hein G. Gooszen5, C.J.H.M. van Laarhoven1
1Department of Surgery, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands
2Department of Surgery, St Elisabeth Hospital, Tilburg, The Netherlands
3Centre of Research on Psychology in Somatic diseases, Tilburg University, Tilburg, the Netherlands
4Medical Psychology, St Elisabeth Hospital, Tilburg, The Netherlands
5Department of Operating Rooms/Evidence-Based Surgery, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands

Tóm tắt

Abstract Background Ileal pouch–anal anastomosis (IPAA) is considered the surgical treatment of choice for patients with ulcerative colitis. Quality of life (QoL) and health status are the most important patient-related outcomes. Studies investigating QoL are often cross-sectional and focus on health status. This longitudinal study evaluated QoL and health status after IPAA for ulcerative colitis and compared these with reference data from a healthy population. Methods Patients with ulcerative colitis who underwent a pouch operation between 2003 and 2008 completed validated questionnaires for QoL and health status. Questionnaires were completed before pouch surgery, and 6, 12, 24 and 36 months after operation. The effect of IPAA on QoL and health status was analysed, and data were compared with reference values from the healthy Dutch population. Results Data were obtained for 30 of the 32 patients. Six months after IPAA, QoL was at least comparable with that of the reference population in four of six domains. Twelve months after IPAA, overall QoL had improved, supported by findings in three QoL domains. Six months after IPAA, health status was comparable to that of the reference population in three of eight dimensions, and after 3 years it was at least comparable in five dimensions. Conclusion QoL and health status increased after IPAA and reached levels comparable with those of the healthy reference population in a majority of domains and dimensions. QoL was restored first after IPAA, followed by health status.

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British Journal of Surgery

Tập 99 Số 2

263-269

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