PySCeSToolbox: a collection of metabolic pathway analysis tools

Bioinformatics (Oxford, England) - Tập 34 Số 1 - Trang 124-125 - 2018
Carl D. Christensen1, Jan‐Hendrik S. Hofmeyr2,1, Johann M. Rohwer1
1Department of Biochemistry, Laboratory for Molecular Systems Biology, Stellenbosch University, South Africa
2Centre for Complex Systems in Transition, School of Public Leadership, Stellenbosch University, Stellenbosch, South Africa

Tóm tắt

Abstract Summary PySCeSToolbox is an extension to the Python Simulator for Cellular Systems (PySCeS) that includes tools for performing generalized supply–demand analysis, symbolic metabolic control analysis, and a framework for investigating the kinetic and thermodynamic aspects of enzyme-catalyzed reactions. Each tool addresses a different aspect of metabolic behaviour, control, and regulation; the tools complement each other and can be used in conjunction to better understand higher level system behaviour. Availability and implementation PySCeSToolbox is available on Linux, Mac OS X and Windows. It is licensed under the BSD 3-clause licence. Code, setup instructions and a link to documentation can be found at https://github.com/PySCeS/PyscesToolbox. Supplementary information Supplementary data are available at Bioinformatics online.

Từ khóa


Tài liệu tham khảo

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Thông tin
Thông tin xuất bản

Bioinformatics (Oxford, England)

Tập 34 Số 1

124-125

Thông tin tác giả