Psychological and Behavioral Predictors of Vaccine Efficacy: Considerations for COVID-19

Perspectives on Psychological Science - Tập 16 Số 2 - Trang 191-203 - 2021
Annelise A. Madison1,2, M. Rosie Shrout2, Megan E. Renna3,2
1Department of Psychology, The Ohio State University
2The Institute for Behavioral Medicine Research, The Ohio State University College of Medicine
3The Comprehensive Cancer Center, The Ohio State University College of Medicine

Tóm tắt

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccine candidates are being evaluated, with the goal of conferring immunity on the highest percentage of people who receive the vaccine as possible. It is noteworthy that vaccine efficacy depends not only on the vaccine but also on characteristics of the vaccinated. Over the past 30 years, a series of studies has documented the impact of psychological factors on the immune system’s vaccine response. Robust evidence has demonstrated that stress, depression, loneliness, and poor health behaviors can impair the immune system’s response to vaccines, and this effect may be greatest in vulnerable groups such as the elderly. Psychological factors are also implicated in the prevalence and severity of vaccine-related side effects. These findings have generalized across many vaccine types and therefore may be relevant to the SARS-CoV-2 vaccine. In this review, we discuss these psychological and behavioral risk factors for poor vaccine responses, their relevance to the COVID-19 pandemic, as well as targeted psychological and behavioral interventions to boost vaccine efficacy and reduce side effects. Recent data suggest these psychological and behavioral risk factors are highly prevalent during the COVID-19 pandemic, but intervention research suggests that psychological and behavioral interventions can increase vaccine efficacy.

Từ khóa


Tài liệu tham khảo

10.1016/j.vaccine.2009.07.055

10.3945/ajcn.115.115188

10.1016/j.bbi.2009.02.018

10.1016/j.bbi.2008.09.007

Burns V. E., 2002, Psychosomatic Medicine, 64, 963

10.1016/j.bbi.2020.04.040

10.1016/j.bbi.2009.10.001

10.1037/0882-7974.7.3.331

Choon Lim Wong G., 2019, Exercise Immunology Review, 25, 20

10.1016/j.immuni.2019.09.020

10.1097/00006842-200101000-00002

10.2105/AJPH.83.9.1277

10.1097/01.PSY.0000077505.67574.E3

10.1016/S0168-8278(86)80051-4

10.1016/j.bbi.2006.04.158

Fitbit Staff, 2020, Fitbit Blog

10.1002/da.23080

10.1111/j.1749-6632.2000.tb06651.x

10.1097/PSY.0b013e31819d1910

10.1016/j.bbi.2008.05.006

10.1016/j.bbi.2007.10.018

10.1038/nri1571

10.1097/00006842-199201000-00005

10.1111/j.1749-6632.1998.tb09603.x

10.1001/archpsyc.60.10.1009

10.1097/00006842-200011000-00010

10.1016/j.bbi.2020.04.069

10.1080/19490976.2017.1376162

10.1542/peds.2013-3937

10.1093/cid/cis1208

10.1016/0022-3999(93)90138-6

10.1093/geronb/gbu006

10.1152/japplphysiol.00790.2006

10.1176/appi.ajp.2015.15020152

10.1073/pnas.93.7.3043

Killgore W. D., 2020, Psychiatry Research, 293

10.1093/gerona/57.9.M557

10.1016/j.eurger.2010.07.002

10.4049/jimmunol.1100015

10.1097/01.PSY.0000091382.61178.F1

10.1016/j.vaccine.2018.09.067

10.1097/PSY.0b013e3180cc2c61

10.1037/amp0000690

Lynn D. J., 2018, Journal of Leukocyte Biology, 103, 225, 10.1189/jlb.5MR0617-216R

10.1037/0278-6133.20.1.4

10.1016/j.bbi.2005.08.009

10.1016/j.vaccine.2013.10.076

10.1097/01.psy.0000116718.54414.9e

10.1016/S0022-3956(99)00010-2

10.1016/j.immuni.2014.08.009

10.4161/hv.28332

10.1016/j.bbi.2013.10.003

10.3390/nu12072016

10.1037/0022-006X.63.5.787

10.1111/j.1469-8986.2005.00281.x

10.1016/j.bbi.2005.08.003

Prather A. A., 2012, Sleep, 35, 1063

10.1098/rstb.2014.0141

10.1037/0278-6133.24.3.297

10.1016/j.neubiorev.2017.01.026

10.1016/j.vaccine.2020.08.043

10.1002/oby.22813

10.3945/jn.109.105312

10.1016/j.bbi.2011.10.009

10.1016/j.bbi.2007.11.004

10.1152/japplphysiol.01404.2003

10.1001/jama.288.12.1469

10.1207/s15327558ijbm1301_8

10.3109/00365549209052627

10.1128/JVI.00781-11

10.1002/da.23077

10.1016/j.vaccine.2019.04.091

10.1159/000071895

10.1016/S0140-6736(98)06098-X

10.1016/j.jaci.2017.10.032

10.1016/0264-410X(94)90283-6

10.1111/j.1532-5415.2009.02563.x

10.1093/gerona/57.9.M563

10.1097/QAD.0000000000001311

Thông tin
Thông tin xuất bản

Perspectives on Psychological Science

Tập 16 Số 2

191-203

Thông tin tác giả