Protective effects of raspberry on the oxidative damage in HepG2 cells through Keap1/Nrf2-dependent signaling pathway

Food and Chemical Toxicology - Tập 133 - Trang 110781 - 2019
Lei Chen1, Kang Li1, Qian Liu1, José L. Quiles2, Rosanna Filosa3, Mohammad Amjad Kamal4,5,6, Fang Wang7, Guoyin Kai8, Xiaobo Zou9, Hui Teng1, Jianbo Xiao9
1College of Food Science, Fujian Agriculture and Forestry University, Fuzhou 350002, China
2Department of Physiology, Institute of Nutrition and Food Technology “Jose Mataix”, Biomedical Research Centre, University of Granada, Armilla, 18100, Granada, Spain
3Department of Experimental Medicine, University of Campania, Via L. De Crecchio 7, Naples, 80138, Italy
4King Fahd Medical Research Center, King Abdulaziz University, P.O. Box 80216, Jeddah 21589, Saudi Arabia
5Enzymoics, 7 Peterlee Place, Hebersham, NSW, 2770, Australia
6Novel Global Community Educational Foundation, Australia
7College of Food Science and Engineering, Nanjing University of Finance and Economics, Nanjing 210023, China
8Laboratory of Medicinal Plant Biotechnology, College of Pharmacy, Zhejiang Chinese Medical University, Hangzhou, Zhejiang, 311402, China
9International Research Center for Food Nutrition and Safety, Jiangsu University, Zhenjiang 212013, China

Tài liệu tham khảo

Bellezza, 2018, Nrf2-Keap1 signaling in oxidative and reductive stress, BBA-Mol Cell Res., 1865, 721 Bobinaitė, 2012, Variation of total phenolics, anthocyanins, ellagic acid and radical scavenging capacity in various raspberry (Rubus spp.) cultivars, Food Chem., 132, 1495, 10.1016/j.foodchem.2011.11.137 Bowen-Forbes, 2010, Anthocyanin content, antioxidant, anti-inflammatory and anticancer properties of blackberry and raspberry fruits, J. Food Compos. Anal., 23, 554, 10.1016/j.jfca.2009.08.012 Breimer, 1990, Molecular mechanisms of oxygen radical carcinogenesis and mutagenesis: the role of DNA base damage, Mol. Carcinog., 3, 188, 10.1002/mc.2940030405 Cao, 2018, Dietary polyphenols for managing type 2 diabetes: human studies and clinical trials, Crit. Rev. Food Sci. Nutr. Chae, 2014, Hepatoprotective effects of Rubus coreanus Miquel concentrates on liver injuries induced by carbon tetrachloride in rats, Nutr Res Pract, 8, 40, 10.4162/nrp.2014.8.1.40 Chen, 2018, Modifications of dietary flavonoids towards improved bioactivity: an update on structure-activity relationship, Crit. Rev. Food Sci. Nutr., 58, 513, 10.1080/10408398.2016.1196334 Choi, 2016, Protective effect of black raspberry seed containing anthocyanins against oxidative damage to DNA, protein, and lipid, J. Food Sci. Tech. Mys., 53, 1214, 10.1007/s13197-015-2094-7 Clarke, 2016, Roles of Nrf2 in drug and chemical toxicity, Curr Opi. Toxicol, 1, 104, 10.1016/j.cotox.2016.10.004 Coates, 2007, Colon-available raspberry polyphenols exhibit anti-cancer effects on in vitro models of colon cancer, J. Carcinog., 6, 10.1186/1477-3163-6-4 Dragan, 2019, Benefits of multiple micronutrient supplementation in heart failure: a comprehensive review, Crit. Rev. Food Sci. Nutr., 59, 965, 10.1080/10408398.2018.1540398 de Sá, 2014, Antioxidant potential and vasodilatory activity of fermented beverages of jabuticaba berry (Myrciaria jaboticaba), J Funct. Foods., 8, 169, 10.1016/j.jff.2014.03.009 Gachou, 1999, The protective activity of α-hederine against H 2 O 2 genotoxicity in HepG2 cells by alkaline comet assay, Mutat Res-Gen Tox En., 445, 9, 10.1016/S1383-5718(99)00117-5 Granado-Serrano, 2012, Quercetin modulates Nrf2 and glutathione-related defenses in HepG2 cells: involvement of p38, Chem. Biol. Interact., 195, 154, 10.1016/j.cbi.2011.12.005 Gowd, 2019, Antioxidant potential and phenolic profile of blackberry anthocyanin extract followed by human gut microbiota fermentation, Food Res. Int., 120, 523, 10.1016/j.foodres.2018.11.001 Jiménez-Aspee, 2016, The Chilean wild raspberry (Rubus geoides Sm.) increases intracellular GSH content and protects against H2O2 and methylglyoxal-induced damage in AGS cells, Food Chem., 194, 908, 10.1016/j.foodchem.2015.08.117 Khan, 2016, Anthocyanins protect against LPS-induced oxidative stress-mediated neuroinflammation and neurodegeneration in the adult mouse cortex, Neurochem. Int., 100, 1, 10.1016/j.neuint.2016.08.005 Khan, 2019, Anti-cancer effects of polyphenols via targeting p53 signaling pathway: updates and future directions, Biotechnol. Adv., 10.1016/j.biotechadv.2019.04.007 Kim, 2017, Effects of Korean ginseng berry on skin antipigmentation and antiaging via FoxO3a activation, J Gins Res, 41, 277, 10.1016/j.jgr.2016.05.005 Kobayashi, 2005, Molecular mechanisms activating the Nrf2-Keap1 pathway of antioxidant gene regulation, Antioxidants Redox Signal., 7, 385, 10.1089/ars.2005.7.385 Lee, 2011, Effects of a Rubus coreanus Miquel supplement on plasma antioxidant capacity in healthy Korean men, Nutr Res Pract, 5, 429, 10.4162/nrp.2011.5.5.429 Lee, 2015, Anti‐inflammatory effect of black raspberry seed oil in high‐fat diet‐induced obese mice, J. Food Biochem., 39, 612, 10.1111/jfbc.12169 Li, 2016, Rapid identification of flavonoid constituents directly from PTP1B inhibitive extract of raspberry (Rubus idaeus L.) leaves by HPLC-ESI-QTOF-MS-MS, J. Chromatogr. Sci., 54, 805, 10.1093/chromsci/bmw016 Liang, 2013, Dihydroquercetin (DHQ) induced HO-1 and NQO1 expression against oxidative stress through the Nrf2-dependent antioxidant pathway, J. Agric. Food Chem., 61, 2755, 10.1021/jf304768p Ma, 2013, Role of nrf2 in oxidative stress and toxicity, Annu. Rev. Pharmacol., 53, 401, 10.1146/annurev-pharmtox-011112-140320 Medzhitov, 2008, Origin and physiological roles of inflammation, Nature, 454, 10.1038/nature07201 Nguyen, 2009, The Nrf2-antioxidant response element signaling pathway and its activation by oxidative stress, J. Biol. Chem., 284, 13291, 10.1074/jbc.R900010200 Nishimura, 2017, Effect of quercetin on cell protection via erythropoietin and cell injury of HepG2 cells, Arch. Biochem. Biophys., 636, 11, 10.1016/j.abb.2017.10.013 Noratto, 2017, Red raspberry (Rubus idaeus L.) intake decreases oxidative stress in obese diabetic (db/db) mice, Food Chem., 227, 305, 10.1016/j.foodchem.2017.01.097 Peiffer, 2018, Preparing black raspberry components for their use as cancer therapeutics, J. Berry Res., 8, 297, 10.3233/JBR-180364 Pitocco, 2013, Oxidative stress in diabetes: implications for vascular and other complications, Int. J. Mol. Sci., 14, 21525, 10.3390/ijms141121525 Poprac, 2017, Targeting free radicals in oxidative stress-related human diseases, Trends Pharmacol. Sci., 38, 592, 10.1016/j.tips.2017.04.005 Qi, 2017, Asiatic acid enhances Nrf2 signaling to protect HepG2 cells from oxidative damage through Akt and ERK activation, Biomed. Pharmacother., 88, 252, 10.1016/j.biopha.2017.01.067 Ramyaa, 2014, Quercetin modulates OTA-induced oxidative stress and redox signalling in HepG2 cells—up regulation of Nrf2 expression and down regulation of NF-κB and COX-2, Bba-Gen subjects, 1840, 681, 10.1016/j.bbagen.2013.10.024 Sies, 2017, Hydrogen peroxide as a central redox signaling molecule in physiological oxidative stress: oxidative eustress, Redox Bio, 11, 613, 10.1016/j.redox.2016.12.035 Sun, 2013, Oxidization resistance in vivo for raspberry flavone, Eng. Times, 5 Sun, 2016, Activation of the p62‐Keap1‐NRF2 pathway protects against ferroptosis in hepatocellular carcinoma cells, Hepatology, 63, 173, 10.1002/hep.28251 Teng, 2013, Optimization of microwave‐assisted extraction for anthocyanins, polyphenols, and antioxidants from raspberry (Rubus Coreanus Miq.) using response surface methodology, J. Sep. Sci., 36, 3107, 10.1002/jssc.201300303 Teng, 2017, Red raspberry and its anthocyanins: bioactivity beyond antioxidant capacity, Trends Food Sci. Technol., 66, 153, 10.1016/j.tifs.2017.05.015 Teng, 2016, Ultrasonic-assisted extraction of raspberry seed oil and evaluation of its physicochemical properties, fatty acid compositions and antioxidant activities, PLoS One, 11, 10.1371/journal.pone.0153457 Xiao, 2015, Stability of dietary polyphenols under the cell culture condition: avoiding erroneous conclusions, J. Agric. Food Chem., 63, 1547, 10.1021/jf505514d Xiao, 2016, Advance on the flavonoid C-glycosides and health benefits, Crit. Rev. Food Sci. Nutr., 56, S29, 10.1080/10408398.2015.1067595 Xiao, 2017, Dietary flavonoid aglycones and their glycosides: which show better biological significance?, Crit. Rev. Food Sci. Nutr., 57, 1874 Xiao, 2018, Stability of dietary polyphenols: it's never too late to mend?, Food Chem. Toxicol., 119, 3, 10.1016/j.fct.2018.03.051 Xu, 2016, Quercetin phospholipid complex significantly protects against oxidative injury in ARPE-19 cells associated with activation of Nrf2 pathway, Eur. J. Pharmacol., 770, 1, 10.1016/j.ejphar.2015.11.050 Zhang, 2016, Wheat bran feruloyl oligosaccharides ameliorate AAPH-induced oxidative stress in HepG2 cells via Nrf2 signaling, J Funct Foods, 25, 333, 10.1016/j.jff.2016.06.012 Zhao, 2019, Regulation of glucose metabolism by bioactive phytochemicals for the management of type 2 diabetes mellitus, Crit. Rev. Food Sci. Nutr., 59, 830, 10.1080/10408398.2018.1501658 Zhao, 2018, Bioactive compounds from marine macroalgae and their hypoglycemic benefits, Trends Food Sci. Technol., 72, 1, 10.1016/j.tifs.2017.12.001 Zinellu, 2017, Blood global DNA methylation is decreased in non-severe chronic obstructive pulmonary disease (COPD) patients, Pulm. Pharmacol. Ther., 46, 11, 10.1016/j.pupt.2017.08.006 Zamora-Ros, 2016, Dietary polyphenol intake in Europe: the European prospective investigation into cancer and nutrition (EPIC) study, Eur. J. Nutr., 55, 1359, 10.1007/s00394-015-0950-x