Primary lymphocutaneous nocardiosis in an immunocompetent patient

Springer Science and Business Media LLC - 2004
Sofia Maraki1, Stavros Chochlidakis2, Eleni Nioti1, Yannis Tselentis1
1Department of Clinical Bacteriology, Parasitology, Zoonoses and Geographical Medicine, University Hospital of Crete, Crete, Greece
2Department of Orthopedics, University Hospital of Crete, Crete, Greece

Tóm tắt

Nocardia brasiliensis is a rare human pathogen usually associated with localized cutaneous infections. We report a case of primary lymphocutaneous Nocardia brasiliensis infection developed after a bone fracture of the left hand of an otherwise healthy 32-year-old man. Treatment with trimethoprim-sulfamethoxazole given for a total of three months combined with surgical debridement resulted in complete resolution of the infection. Nocardiosis should be part of the differential diagnosis in patients with sporotrichoid infection, particularly those with a history of outdoor injury. Culture of the affected tissue and antimicrobial susceptibility testing of the isolate should be performed for diagnosis and treatment.

Từ khóa


Tài liệu tham khảo

Brown JM, McNeil MM, Desmond EP: Nocardia, Rhodococcus, Gordona, Actinomadura, Streptomyces, and other actinomycetes of medical importance. In: Manual of Clinical Microbiology. Edited by: Murray PR, Baron EJ, Pfaller MA, Tenover FC, Yolken RH. 1999, 370-398. Washington, DC: American Society for Microbiology,

Sorrell TC, Iredel JR, Mitchell DH: Nocardia species. In: Principles and Practice of Infectious Diseases. Edited by: Mandell GL, Bennett JE, Dolin R. 2000, 2637-2645. Philadelphia, Churchill Livingstone,

Beaman BL, Burnside J, Edwards B, Causey W: Nocardial infections in the United States, 1972–1974. J Infect Dis. 1976, 134: 286-289.

Boiron P, Provost F, Chevrier G, Dupont B: Review of nocardial infections in France 1987–1990. Eur J Clin Microbiol Infect Dis. 1992, 11: 709-714.

Farina C, Boiron P, Ferrari I, Provost F, Goglio A: Report of human nocardiosis in Italy between 1993 and 1997. Eur J Epidemiol. 2001, 17: 1019-1022. 10.1023/A:1020010826300

Maraki S, Scoulica E, Alpantaki K, Dialynas M, Tselentis Y: Lymphocutaneous nocardiosis due to Nocardia brasiliensis. Diagn Microbiol Infect Dis. 2003, 47: 341-344. 10.1016/S0732-8893(03)00090-7

Smego RA, Gallis HA: The clinical spectrum of Nocardia brasiliensis infections in the United States. Rev Infect Dis. 1984, 6: 164-180.

Smego RA, Castiglia M, Asperilla MO: Lymphocutaneous syndrome. A review of non-sporothrix causes. Medicine. 1999, 78: 38-63. 10.1097/00005792-199901000-00004

Kiska DL, Hicks K, Pettit DJ: Identification of medically relevant Nocardia species with an abbreviated battery of tests. J Clin Microbiol. 2002, 40: 1346-1351. 10.1128/JCM.40.4.1346-1351.2002

Smego RA, Moeller MB, Gallis HA: Trimethoprim-sulfamethoxazole therapy for Nocardia infections. Arch Intern Med. 1983, 143: 711-718. 10.1001/archinte.143.4.711

Nolt D, Wadowsky RM, Green M: Lymphocutaneous Nocardia brasiliensis infection: A pediatric case cured with amoxicillin/clavulanate. Pediatr Infect Dis J. 2000, 19: 1023-1025.

Thông tin
Thông tin xuất bản

Springer Science and Business Media LLC

Thông tin tác giả