Prevalence of Depression and Anxiety in Parkinson Disease and Impact on Quality of Life: A Community-Based Study in Spain

Journal of Geriatric Psychiatry and Neurology - Tập 33 Số 4 - Trang 207-213 - 2020
Fany Chuquilín-Arista1,2, Tania Álvarez-Avellón3, Manuel Menéndez‐González4,5,6
1Community and Family Medicine, Health Area VII, Asturias, Spain
2Health Science Research, University of Valladolid, Spain
3Department of Psychology, Universidad de Oviedo, Asturias, Spain
4Department of Morphology and Cell Biology, Universidad de Oviedo, Asturias, Spain
5Department of Neurology, Hospital Universitario Central de Asturias (HUCA), Oviedo, Asturias, Spain
6Instituto de Salud del Principado de Asturias (ISPA), Oviedo, Asturias, Spain

Tóm tắt

Background:Identifying neuropsychiatric disorders is essential for prompt treatment to reduce morbidity. Among these disorders, anxiety and depression have been frequently associated with Parkinson disease (PD), particularly among elderly population.Objective:The objective of this study is to determine the prevalence of anxiety and depression in a series of community-based PD cases in Spain, their relationship with different clinical and sociodemographic characteristics, and quality of life.Methods:This is an observational, descriptive, survey-based study with 95 community-based patients with PD diagnosis at different disease stages. Anxiety and depression were assessed using the State-Trait Anxiety Inventory and the Beck Depression Inventory II, respectively. Quality of life was assessed using the Parkinson’s Disease Questionnaire 39.Results:The prevalence of depression and anxiety was 32.63% and 68.42%, respectively. Concomitant depression and anxiety were observed in 31.58% of patients. Patients with longer than 10 years’ PD duration had an increased risk of depression. We found a relationship between the presence of anxiety, depression, and the patient’s quality of life.Conclusions:Depression is present in one-third and anxiety in two-thirds of PD cases in community settings in Spain. Depression and anxiety have a very negative impact on quality of life in PD. Both anxiety and depression are independent from sociodemographic characteristics, patient’s comorbidities, or antiparkinsonian treatments; presenting as intrinsic symptoms in PD.

Từ khóa


Tài liệu tham khảo

Glaría BG, 2010, Tratado de Neuropsicogeriatría, 267

10.1002/mds.21803

Pincus JH, Tucker GJ. Behavioral Neurology. 4th ed. New York, NY: Oxford University Press; 2002: 177–195.

10.2169/internalmedicine.52.8617

10.4103/0253-7176.155611

10.1176/jnp.2009.21.4.413

Spielberg CD, 1994, Cuestionario De Ansiedad Estado-Rasgo. Manual, 4

10.1371/journal.pone.0189682

10.1159/000478849

10.2147/NDT.S132757

10.1016/j.jad.2011.01.021

10.1111/j.1468-1331.2004.00781.x

Álvarez-Avellón T, 2015, J Neurol Neurosci, 1, 1

Aguilar M., 2018, Proceedings of the 22TH International Congress of Parkinson’s Disease and Movement Disorders

10.1002/mds.22760

10.1186/s12877-017-0666-2

10.1136/pmj.77.904.89

Errea JM, 1999, Rev Neurol, 28, 694

10.1155/2017/1470149

10.1016/j.parkreldis.2016.12.026

10.1016/j.jagp.2013.09.006

10.1177/0891988718757369

Stella F, 2007, Rev Neurol, 45, 594

10.1002/mds.22833

10.1002/mds.26461

10.1212/WNL.0b013e3182a4a503

Heller J, 2014, Aging Dis, 5, 63

10.1111/ane.12796

10.1007/s00702-005-0285-5

10.1017/S1041610215002410

10.1371/journal.pone.0178896

Thông tin
Thông tin xuất bản

Journal of Geriatric Psychiatry and Neurology

Tập 33 Số 4

207-213

Thông tin tác giả