Preterm neonates benefit from low prophylactic platelet transfusion threshold despite varying risk of bleeding or death
Susanna F. Fustolo-Gunnink1,2,3, Karin Fijnvandraat2,4, David van Klaveren5,6, Simon J. Stanworth7,8,9, Anna Curley10, Wes Onland11, Ewout W. Steyerberg12, Ellen de Kort13, Esther J. d'Haens14, Christian V. Hulzebos15, Elise J. Huisman16, Willem P. de Boode17, Enrico Lopriore18, Johanna G. van der Bom1,3
1Center for Clinical Transfusion Research, Sanquin Research, Leiden, the Netherlands
2Pediatric Hematology, Emma Children's Hospital, Amsterdam University Medical Center (UMC), University of Amsterdam, The Netherlands
3Department of Epidemiology, Leiden University Medical Center, Leiden, the Netherlands
4Department of Molecular Cellular Hemostasis, Sanquin Research, Amsterdam, The Netherlands
5Department of Public Health, Erasmus University Medical Center, Rotterdam, The Netherlands
6Predictive Analytics and Comparative Effectiveness Center, Tufts Medical Center, Boston, MA
7Transfusion Medicine, National Health Service (NHS) Blood and Transplant, Oxford, United Kingdom
8Department of Haematology, Oxford University Hospitals NHS Foundation Trust, Oxford, United Kingdom
9Radcliffe Department of Medicine, Biomedical Research Centre (BRC) Haematology Theme, University of Oxford, Oxford, United Kingdom
10Department of Neonatology, National Maternity Hospital, Dublin, Ireland
11Department of Neonatology, Emma Children's Hospital, Amsterdam UMC, Amsterdam, The Netherlands
12Department of Biomedical Data Sciences, Leiden University Medical Center, Leiden, the Netherlands
13Department of Neonatology, Máxima Medical Center, Veldhoven, The Netherlands
14Department of Neonatology, Amalia Children's Center, Zwolle, The Netherlands
15Department of Neonatology, Beatrix Children's Hospital, University Medical Center Groningen, Groningen, The Netherlands
16Department of Pediatric Hematology, Erasmus Medical Center ‐ Sophia Children's Hospital, Rotterdam, The Netherlands
17Department of Neonatology, Radboud University Medical Center, Nijmegen, The Netherlands
18Division of Neonatology, Department of Pediatrics, Leiden University Medical Center, Leiden, The Netherlands