Presence of Streptococcus DNA Sequence in Surgical Specimens of Gastric Cancer

Wiley - Tập 86 Số 9 - Trang 791-794 - 1995
Hiroki Sasaki1, Hiroyasu Igaki2, Tomoki Ishizuka2, Yukiko Kogoma2, Takashi Sügimura2, Masaaki Terada2
1Genetics Division, National Cancer Center Research Institute, Tokyo.
2Genetics Division, National Cancer Center Research Institute, 1–1 Tsukiji 5‐chotne, Chuo‐ku, Tokyo 104

Tóm tắt

In Southern blot analysis using Mycoplasma16S ribosomal DNA (rDNA) as a probe, positive signals were detected in DNA samples from surgical specimens of gastric cancers. The DNA that hybridized to Mycoplasma 16S rDNA was eluted from the gel, cloned and sequenced. The cloned sequence was identical to 16S rDNA of Streptococcus anginosus. In Southern blot analysis with the S. anginosus 16S rDNA fragment as a new probe, positive signals were detected in 9 (20%) out of 43 cases of gastric cancer.

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