Preliminary evidence for the effects of environmental complexity on hybridization of rat brain RNA to rat unique DNA

Developmental Psychobiology - Tập 8 Số 2 - Trang 171-178 - 1975
Lynda Uphouse1,2, James Bonner2
1Department of Psychology, Yale University, New Haven, Connecticut 06520, U.S.A.
2Division of Biology, California Institute of Technology, Pasadena, California

Tóm tắt

AbstractHybridization to unique DNA by RNA from brain or liver of rats given varying degrees of experience was investigated. RNA from brain of environmentally enriched rats hybridized to more unique DNA than did brain RNA from nonenriched controls. No significant differences were observed with liver RNA. This provides preliminary evidence for an increased transcription of the unique sequences of DNA in the enriched animals. The technique used has great promise for the investigation of experientially‐induced alterations in gene expression.

Từ khóa


Tài liệu tham khảo

10.1007/978-1-4684-6042-1_16

Britten R. J., 1967, Nucleotide sequence repetition in DNA Carnegie, Inst. Washington Yearbook, 65, 78

10.1016/0006-291X(71)90508-0

10.1021/bi00787a005

10.1016/0022-2836(73)90359-8

10.1146/annurev.bi.38.070169.003133

10.1021/bi00755a019

10.1126/science.173.3992.158

10.1038/229114b0

10.1038/222573a0

10.1111/j.1471-4159.1973.tb12130.x

10.1007/BF01066705

10.1016/0022-2836(72)90330-0

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Developmental Psychobiology

Tập 8 Số 2

171-178

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