Preliminary Results with Percutaneous Transcatheter Microwave Ablation of Typical Atrial Flutter

Journal of Cardiovascular Electrophysiology - Tập 18 Số 3 - Trang 286-289 - 2007
Joseph Yat‐Sun Chan1, Jeffery Fung1, Cheuk‐Man Yu1, Gregory K. Feld2
1Department of Medicine & Therapeutics, Prince of Wales Hospital, The Chinese University of Hong Kong, Hong Kong SAR, China
2Department of Medicine, Division of Cardiology, University of California, San Diego, California, USA

Tóm tắt

Background: Linear microwave ablation has been shown to be effective for treatment of atrial fibrillation during open‐heart surgery by producing transmural lesions in the atrium to isolate the pulmonary veins. However, the safety and efficacy of percutaneous, transcatheter, linear microwave ablation for atrial arrhythmias, while demonstrated in animal models, is unknown in humans. Therefore, we studied the safety and efficacy of linear microwave ablation of the cavotricuspid isthmus (CTI) in humans with typical atrial flutter, utilizing a 2‐cm long microwave antenna mounted on a steerable 9‐French catheter. Methods and Results: In seven consecutive patients, multielectrode catheters were positioned at the His bundle (quadripolar) and around the TV annulus (duo‐decapolar) for pacing and recording atrial activation sequence before and after ablation. The microwave antenna was withdrawn gradually from tricuspid annulus towards inferior vena cava to ablate the CTI. Intracardiac ultrasound was used to ensure adequate endocardial contact of the microwave ablation catheter with the CTI. Microwave energy was applied at a power of 18 to 21 W at each ablation point for 120 seconds. Ablation was repeated until bidirectional CTI block was confirmed by demonstrating a descending activation wavefront in the contralateral atrial wall during pacing from the coronary sinus ostium or low lateral right atrium, respectively. Bidirectional isthmus block was achieved in all patients, after a mean number of 27.4 ± 14.7 energy applications per patients. There were no acute procedural complications. Conclusions: Percutaneous, transcatheter microwave ablation of CTI dependent atrial flutter was demonstrated to be safe and effective in this preliminary feasibility study.

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Thông tin xuất bản

Journal of Cardiovascular Electrophysiology

Tập 18 Số 3

286-289

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