Predisposition to Obesity: Should We Target Those Most Susceptible?
Tóm tắt
Obesity prevention should remain a priority, even if there is some suggestion that the epidemic may presently have reached a stable level. However, previous interventions have not been effective in preventing overweight and obesity, and at the same time studies suggest that some subgroups are more predisposed to future obesity. The purpose of this paper is to review interventions on obesity prevention published during the past year, and to examine if interventions targeting predisposed groups or individuals seem more efficient in preventing obesity than studies targeting general populations. Among 15 identified studies, 7 targeted predisposed children or adolescents. More of the studies targeting predisposed individuals were able to show significant effects than the studies targeting general populations. Most studies targeting predisposed defined the predisposition based on ethnicity or socioeconomic status. Thus, we may be more successful in preventing obesity when targeting predisposed individuals, but more studies are needed before a firm conclusion can be drawn.
Tài liệu tham khảo
World Health Organization. Obesity: preventing and managing the global epidemic. Report of a WHO consultation on Obesity. 2000, 840. WHO Technical Report Series.
• Rokholm B, Baker JL, Sorensen TI. The levelling off of the obesity epidemic since the year 1999–a review of evidence and perspectives. Obes Rev. 2010;11:835–46. This study found that even though the obesity epidemic may be taking a break, previous stable phases have been followed by further increases. Therefore, obesity prevention should remain a priority.
Summerbell CD, Waters E, Edmunds LD, et al. Interventions for preventing obesity in children. Cochrane Database Syst Rev. 2005;CD001871.
Newell A, Zlot A, Silvey K, Arail K. Addressing the obesity epidemic: a genomics perspective. Prev Chronic Dis. 2007;4:A31.
Danielzik S, Czerwinski-Mast M, Langnase K, et al. Parental overweight, socioeconomic status and high birth weight are the major determinants of overweight and obesity in 5-7 y-old children: baseline data of the Kiel Obesity Prevention Study (KOPS). Int J Obes Relat Metab Disord. 2004;28:1494–502.
• Deboer MD. Ethnicity, obesity and the metabolic syndrome: implications on assessing risk and targeting intervention. Expert Rev Endocrinol Metab. 2011;6:279–89. This study reviews ethnicity and obesity in children, and brings attention to the applicability of ethnicity as a determinant for predisposition to overweight and obesity.
Sørensen TIA. Challenges in the study of causation of obesity. Proc Nutr Soc. 2009;68:43–54.
Balas-Nakash M, Itez-Arciniega A, Perichart-Perera O, et al. The effect of exercise on cardiovascular risk markers in Mexican school-aged children: comparison between two structured group routines. Salud Publica Mex. 2010;52:398–405.
Foster GD, Linder B, Baranowski T, et al. A school-based intervention for diabetes risk reduction. N Engl J Med. 2010;363:443–53.
Tucker S, Lanningham-Foster L, Murphy J, et al. A school based community partnership for promoting healthy habits for life. J Community Health. 2011;36:414–22.
Hawthorne A, Shaibi G, Gance-Cleveland B, McFall S. Grand Canyon Trekkers: school-based lunchtime walking program. J Sch Nurs. 2011;27:43–50.
• Lubans DR, Morgan PJ, Aguiar EJ, Callister R. Randomized controlled trial of the Physical Activity Leaders (PALs) program for adolescent boys from disadvantaged secondary schools. Prev Med. 2011;52:239–46. This study targeted individuals predisposed to future overweight and obesity and found the strongest effect of the intervention on BMI, BMI z-scores, and body fat.
Hoffman JA, Thompson DR, Franko DL, et al. Decaying behavioral effects in a randomized, multi-year fruit and vegetable intake intervention. Prev Med. 2011;52:370–5.
Neumark-Sztainer DR, Friend SE, Flattum CF, et al. New moves-preventing weight-related problems in adolescent girls a group-randomized study. Am J Prev Med. 2010;39:421–32.
Hendy HM, Williams KE, Camise TS. Kid’s Choice Program improves weight management behaviors and weight status in school children. Appetite. 2011;56:484–94.
Nemet D, Geva D, Eliakim A. Health promotion intervention in low socioeconomic kindergarten children. J Pediatr. 2011;158:796–801.
Paul IM, Savage JS, Anzman SL, et al. Preventing obesity during infancy: a pilot study. Obesity (Silver Spring). 2011;19:353–61.
Wake M, Price A, Clifford S, et al. Does an intervention that improves infant sleep also improve overweight at age 6? Follow-up of a randomised trial. Arch Dis Child. 2011;96:526–32.
Klesges RC, Obarzanek E, Kumanyika S, et al. The Memphis Girls’ health Enrichment Multi-site Studies (GEMS): an evaluation of the efficacy of a 2-year obesity prevention program in African American girls. Arch Pediatr Adolesc Med. 2010;164:1007–14.
Luoto R, Kalliomaki M, Laitinen K, Isolauri E. The impact of perinatal probiotic intervention on the development of overweight and obesity: follow-up study from birth to 10 years. Int J Obes (Lond). 2010;34:1531–7.
Karanja N, Lutz T, Ritenbaugh C, et al. The TOTS community intervention to prevent overweight in American Indian toddlers beginning at birth: a feasibility and efficacy study. J Community Health. 2010;35:667–75.
Robinson TN, Matheson DM, Kraemer HC, et al. A randomized controlled trial of culturally tailored dance and reducing screen time to prevent weight gain in low-income African American girls: Stanford GEMS. Arch Pediatr Adolesc Med. 2010;164:995–1004.
Bressler J, Kao WH, Pankow JS, Boerwinkle E. Risk of type 2 diabetes and obesity is differentially associated with variation in FTO in whites and African-Americans in the ARIC study. PLoS One. 2010;5:e10521.
Rugholm S, Baker JL, Olsen LW, et al. Stability of the association between birth weight and childhood overweight during the development of the obesity epidemic. Obes Res. 2005;13:2187–94.
The Danish Board of Technology. Targeted prevention of obesity - more effect for the money. 2011.
Monasta L, Batty GD, Macaluso A, et al. Interventions for the prevention of overweight and obesity in preschool children: a systematic review of randomized controlled trials. Obes Rev. 2011;12:e107–18.
Loos RJ. Recent progress in the genetics of common obesity. Br J Clin Pharmacol. 2009;68:811–29.