Sarah E. Ackerman, Olivia A. Blackburn, François Marchildon, Paul Cohen
Adipocytes have adapted to store energy in the form of lipid and also secrete
circulating factors called adipokines that signal to other tissues to coordinate
energy homeostasis. These functions are disrupted in the setting of obesity,
promoting the development of diseases such as diabetes, cardiovascular disease,
and cancer. Obesity is linked to an increased risk of many types of cancer and
incre... hiện toàn bộ
Samuel Joshua Pragasam Sampath, Vijayalakshmi Venkatesan, Sudip Ghosh, Nagasuryaprasad Kotikalapudi
Metabolic syndrome (MetS), also called the ‘deadly quartet’ comprising obesity,
diabetes, dyslipidemia, and hypertension, has been ascertained to have a causal
role in the pathogenesis of osteoarthritis (OA). This review is aimed at
discussing the current knowledge on the contribution of metabolic syndrome and
its various components to OA pathogenesis and progression. Lately, an increased
associat... hiện toàn bộ