Pre- and postnatal toxicity of the commercial glyphosate formulation in Wistar rats

Fühner-Wieland's Sammlung von Vergiftungsfällen - Tập 81 Số 9 - Trang 665-673 - 2007
Eliane Dallegrave1, Fabiana DiGiorgio Mantese1, Rosemari Terezinha de Oliveira1, Anderson Joel Martino‐Andrade2, Paulo Roberto Dalsenter2, Augusto Langeloh1
1Federal University of Rio Grande do Sul
2Federal University of Paranà

Tóm tắt

Từ khóa


Tài liệu tham khảo

Akingbemi BT, Hardy MP (2001) Oestrogenic and antiandrogenic chemicals in the environment: effects on male reproductive health. Ann Med 33(8):391–403

Amann RP (1982) Use of animal models for detecting specific alterations in reproduction. Fundam Appl Toxicol 2:13–26

Amann RP, Johnson L, Thompson Jr DL, Pickett BW (1976) Daily spermatozoal production, epididymal spermatozoal reserves and transit time of spermatozoa through the epididymis of the rhesus monkey. Biol Reprod 15:586–592

Baker VA (2001) Endocrine disrupters—testing strategies to assess human hazard. Toxicol In Vitro 15:413–419

Baker HJ, Lindsey JR, Weisbroth SH (1980) The laboratory rat. Research applications. Academics, New York

Dallegrave E, Mantese FDG, Dalsenter PR, Langeloh A (2002) Acute oral toxicity of glyphosate in Wistar rats. Online J Vet Res 1:29–36. Available at http://www.cpb.uokhsc.edu/ojvr/absglyphosate.htm

Dallegrave E, Mantese FDG, Coelho RS, Pereira JD, Dalsenter PR, Langeloh A (2003) The teratogenic potential of the herbicide glyphosate-Roundup® in Wistar rats. Toxicol Lett 142:45–52

Dalsenter PR, Dallegrave E, Mello JRB, Langeloh A, Oliveira RT, Faqui AS (1999) Reproductive effects of endosulfan on male offspring of rats exposed during pregnancy and lactation. Hum Exp Toxicol 18:583–589

EDSTAC—Endocrine Disruptor and Testing Advisory Committee (1998) Final Report. EPA/743/R-98/003

Gray Jr LE (1998) Tiered screening and testing strategy for xenoestrogens and antiandrogens. Toxcol Lett 102–103:677–680

Kelly DD (1991) Sexual differentiation of the nervous system. In: Kandel E, Schwartz JH, Jessell TM (eds) Principles of neural science, 3rd edn. Prentice-Hall, Connecticut, pp 959–973

Mably TA, Moore RW, Peterson RE (1992) In utero and lactational exposure of male rats to 2,3,7,8-tetrachlorodibenzo-p-dioxin. Toxicol Appl Pharmacol 114:97–107

Martinez TT, Long WC, Hiller H (1990) Comparison of the toxicology of herbicide Roundup by the oral and pulmonary routes of exposure. Proc West Pharmacol Soc 33:193–197

Massaad C, Barouki R (1999) An assay for the detection of xenoestrogens based on a promoter containing overlapping EREs. Environ Health Perspect 107(7):563–566

Menkes DB, Temple WA, Edwards IR (1991) Intentional self-poisoning with glyphosate-containing herbicides. Hum Exp Toxicol 10:103–107

Morrissey RE, Schwetz BA, Lamb JC, Ross MD, Teague JL, Morris RW (1988) Evaluation of rodent sperm, vaginal cytology, and reproductive organ weight data from National Toxicology Program 13-week studies. Fundam Appl Toxicol 11:343–358

Paumgartten FRJ, De-Carvalho RR, Souza CAM, Madi K, Chahoud I (1997) Study of the effects of β-myrcene on rat fertility and general reproductive performance. Braz J Med Biol Res 31:955–965

Richard S, Moslemi S, Sipahutar H, Benachour, Seralini GE (2005) Differential effects of glyphosate and Roundup® on human placental cells and aromatase. Environ Health Perspect 113:716–720

Robb GW, Amann RP, Killian GJ (1978) Daily sperm production and epididymal sperm reserves of pubertal and adult rats. J Reprod Fertil 54:103–107

Russell LD, Ettlin RA, Sinha-Hikim AP, Clegg ED (1990) Histological and histopathological evaluation of the testis. Cache River, Clearwater, pp 210–264

Smith EA, Oehme FW (1992) The biological activity of glyphosate to plants and animals: a literature review. Vet Hum Toxicol 34(6):531–543

US EPA—Environmental Protection Agency (1996) Guidelines for Reproductive Toxicity Risk Assessment. EPA/630/R-96/009. Washington, DC

Waller DP, Killinger JM, Zaneveld LJD (1995) Physiology and toxicology of male reproductive tract. In: Thomas JA et al (eds) Endocrine toxicology. Raven, New York, pp 269–333

Walsh LP, McCormick C, Martin C, Stocco DM (2000) Roundup inhibits steroidogenesis by disrupting steroidogenic acute regulatory (StAR) protein expression. Environ Health Perspect 108:769–776

Williams GM, Kroes R, Munro IC (2000) Safety evaluation and risk assessment of herbicide Roundup and its active ingredient, glyphosate, for humans. Regul Toxicol Pharmacol 31:117–165

Wilson JD, George FW, Griffin JE (1981) The hormonal control of sexual development. Sci 211:1278–1284

WHO—World Health Organization (1994) Glyphosate. Environ Health Criteria 159:1–177

WHO—World Health Organization (2001) Principles for evaluating health risks to reproduction associated with exposure to chemicals. Environ Health Criteria 225:1–181

Yousef MI, Salem MH, Bertheussen K (1995) Toxic effects of carbofuran and glyphosate on semen characteristics in rabbits. J. Environ Sci Health B 30(4):513–534