Practical Methods for Compensating for Missed Treatment Days in Radiotherapy, with Particular Reference to Head and Neck Schedules

Slevin, 1992, The effects of increasing the treatment time beyond three weeks on the control of T2 and T3 laryngeal cancer using radiotherapy, Radiother Oncol, 24, 215, 10.1016/0167-8140(92)90226-K

Fowler, 2000, Non small cell lung tumours repopulate rapidly during radiation therapy. (Letter), Int J Radiat Oncol Biol Phys, 46, 516, 10.1016/S0360-3016(99)00364-8

Fowler, 2000, Radiobiological modelling to compensate for unplanned gaps in radiation treatment, 653

RCR Ref No BFCO (96) 4, Guidelines for the management of the unscheduled interruption or prolongation of a radical course of radiotherapy, 1996, Royal College of Radiologists

Sinclair, 1999, BED-time charts and their application to the problems of interruptions in external beam radiotherapy treatments, Int J Radiat Onc Biol Physics, 44, 381, 10.1016/S0360-3016(99)00028-0

Wheldon, 1990, Radiobiological rationale for compensation for gaps in radiotherapy regimes by post-gap acceleration of fractionation, Br J Radiol, 63, 114, 10.1259/0007-1285-63-746-114

Dale, 1994, A proposed Figure of Merit for the radiobiological assessment of unscheduled treatment interruptions, Br J Radiol, 67, 1001, 10.1259/0007-1285-67-802-1001

Dale, 2000, Dose-equivalents of tumour repopulation during radiotherapy: the potential for confusion, Br J Radiol, 73, 892, 10.1259/bjr.73.872.11026867

Doerr, 2001, Consequential late effects in normal tissues, Radiother Oncol, 61, 223, 10.1016/S0167-8140(01)00429-7

Fowler, 2000, Confirmation of improved loco-regional control with altered fractionation in head and neck cancer, Int J Radiat Oncol Biol Phys, 48, 3, 10.1016/S0360-3016(00)00643-X

Steel, 1997

Roberts, 1999, Time factors in larynx tumour radiotherapy: Lag times and intertumour heterogeneity in clinical datasets from four centres, Int J Radiat Oncol Biol Phys, 45, 1247, 10.1016/S0360-3016(99)00320-X

Fu, 2000, A Radiation Therapy Oncology Group (RTOG) Phase III randomised study to compare hyperfractionation and two variants of accelerated fractionation to standard fractionation radiotherapy for head and neck squamous cell carcinomas: first report of RTOG 9003, Int J Radiat Oncol Biol Phys, 48, 7, 10.1016/S0360-3016(00)00663-5

Withers, 2000, Transmutability of dose and time. Comments on the 1st report of RTOG 9003 (KK Fu et al), Int J Radiat Oncol Biol Phys, 48, 1, 10.1016/S0360-3016(00)00644-1

Allal, 1999, Avoidance of treatment interruption: an unrecognised benefit of accelerated radiotherapy in oropharyngeal carcinomas?, Int J Radiat Oncol Biol Phys, 45, 41, 10.1016/S0360-3016(99)00138-8

Robertson, 1998, Similar decreases in local control are calculated for treatment protraction and for interruptions in the radiotherapy of carcinoma of the larynx in four centers, Int J Radiat Oncol Biol Phys, 40, 319, 10.1016/S0360-3016(97)00716-5

Robertson, 1998, Effect of gap length and position on results of treatment of cancer of the larynx in Scotland by radiotherapy: a linear quadratic analysis, Radiother.Oncol, 48, 165, 10.1016/S0167-8140(98)00038-3

Baumann, 2001, No evidence for a different magnitude of the time factor for continuously fractionated irradiation and protocols including gaps in two human squamous cell carcinoma in nude mice, Radiother Oncol, 59, 187, 10.1016/S0167-8140(01)00283-3

Zieron, 2001, Impact of the position of a gap on the response of the RIH-tumour of the rat on fractionated split-course radiotherapy, Strahlenther Onkol, 177, 592, 10.1007/PL00002369

Sanguineti, 2001, Lack of a time factor in alternating chemotherapy for advanced head and neck squamous cell carcinoma, Tumori, 87, 10, 10.1177/030089160108700102

Weber, 2001, The impact of gap duration on local control in anal canal carcinoma treated by split-course radiotherapy and concomitant chemotherapy, Int J Radiat Oncol Biol Phys, 50, 675, 10.1016/S0360-3016(01)01510-3

Bentzen, 1992, Overall treatment time and tumour control dose for head and neck tumours: the dog leg revisited, Radiother Oncol, 25, 143, 10.1016/0167-8140(92)90023-N

Mehta, 2001, A new approach to dose escalation in non small cell lung cancer, Int J Radiat Oncol Biol Phys, 49, 23, 10.1016/S0360-3016(00)01374-2

King, 2000, What is the Tpot for prostate cancer? Radiobiological implications of the equivalent outcome with125 I or 103Pd, Int J Radiat Oncol Biol Phys, 47, 1165, 10.1016/S0360-3016(00)00543-5

Bentzen, 1999, Repair halftimes estimated from observations of treatment-related morbidity after CHART or conventional radiotherapy in head and neck cancer, Radiother Oncol, 53, 219, 10.1016/S0167-8140(99)00151-6

Thames, 1987

Fowler, 1999, Is repair of DNA strand break damage from ionizing radiation second order rather than first order? A simpler explanation of apparently multiexponential repair, Radiat Res, 153, 124, 10.2307/3580085

Dale, 1999, A new incomplete-repair model based on a ‘reciprocal-time’ pattern of sub-lethal damage repair, Acta Oncol, 7, 919, 10.1080/028418699432608

Dische, 1989, Continuous, hyperfractionated, accelerated radiotherapy (CHART): an interim report upon late morbidity, Radiother Oncol, 16, 65, 10.1016/0167-8140(89)90071-6

Millar, 1996, Repair kinetics in pig epidermis: an analysis based on two separate rates of repair, Int J Radiat Biol, 69, 123, 10.1080/095530096146255

Jones, 2000, Biological equivalent dose assessment of the consequences of hypofractionated radiotherapy, Int J Radiat Oncol Biol Phys, 47, 1379, 10.1016/S0360-3016(00)00571-X