Postoperative Cognitive Dysfunction after Noncardiac Surgery

Anesthesiology - Tập 106 Số 3 - Trang 572-590 - 2007
Stanton Newman1, Jan Stygall2, Shashivadan P. Hirani3, Shahzad Shaefi4, Mervyn Maze5, David C. Warltier
1Centre for Behavioural & Social Sciences in Medicine, University College London, United Kingdom.
2Senior Research Fellow, Centre for Behavioural and Social Sciences in Medicine, University College London, and Department of Psychology, Thames Valley University, London, United Kingdom.
3Research Fellow.
4Intern in Anesthesiology, Centre for Behavioural and Social Sciences in Medicine, University College London.
5Professor of Anesthesiology, Department of Anaesthetics, Pain Medicine and Intensive Care, Imperial College London, London, United Kingdom.

Tóm tắt

This article describes a systematic review on the research into postoperative cognitive dysfunction (POCD) in noncardiac surgery to ascertain the status of the evidence and to examine the methodologies used in studies. The review demonstrated that in the early weeks after major noncardiac surgery, a significant proportion of people show POCD, with the elderly being more at risk. Minimal evidence was found that patients continue to show POCD up to 6 months and beyond. Studies on regional versus general anesthesia have not found differences in POCD. Many studies were found to be underpowered, and a number of other methodologic difficulties were identified. These include the different types of surgery in studies and variations in the number and range of neuropsychological tests used. A particular issue is the variety of definitions used to classify individuals as having POCD.

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Tài liệu tham khảo

for the Octopus Study Group

ISPOCD Group

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Thông tin xuất bản

Anesthesiology

Tập 106 Số 3

572-590

Thông tin tác giả