Phase Modifiers Promote Efficient Production of Hydroxymethylfurfural from Fructose

American Association for the Advancement of Science (AAAS) - Tập 312 Số 5782 - Trang 1933-1937 - 2006
Yuriy Román‐Leshkov1, Juben N. Chheda1, James A. Dumesic1
1Department of Chemical and Biological Engineering, University of Wisconsin, Madison, WI 53706, USA

Tóm tắt

Furan derivatives obtained from renewable biomass resources have the potential to serve as substitutes for the petroleum-based building blocks that are currently used in the production of plastics and fine chemicals. We developed a process for the selective dehydration of fructose to 5-hydroxymethylfurfural (HMF) that operates at high fructose concentrations (10 to 50 weight %), achieves high yields (80% HMF selectivity at 90% fructose conversion), and delivers HMF in a separation-friendly solvent. In a two-phase reactor system, fructose is dehydrated in the aqueous phase with the use of an acid catalyst (hydrochloric acid or an acidic ion-exchange resin) with dimethylsulfoxide and/or poly(1-vinyl-2-pyrrolidinone) added to suppress undesired side reactions. The HMF product is continuously extracted into an organic phase (methylisobutylketone) modified with 2-butanol to enhance partitioning from the reactive aqueous solution.

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The HMF yield and HMF concentration (in units of g/ml) as reported by different authors in representative systems are presented as follows: Dehydration system: HMF yield HMF concentration (reference numbers). DMSO: >95% <0.13 ( 9 – 12 ); polyethylene glycol/water: 60% 0.28 ( 6 13 ); water 34% <0.06 ( 14 ); water and water-miscible solvents: >75% <0.04 ( 1 10 15 16 ); biphasic systems: >75% <0.02 ( 6 17 – 20 ).

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This work was supported by the U.S. Department of Agriculture and the NSF Chemical and Transport Systems Division of the Directorate for Engineering.

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American Association for the Advancement of Science (AAAS)

Tập 312 Số 5782

1933-1937

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