Pharmacokinetics of Amitriptyline and One of Its Metabolites, Nortriptyline, in Rats: Little Contribution of Considerable Hepatic First-Pass Effect to Low Bioavailability of Amitriptyline Due to Great Intestinal First-Pass Effect
Tài liệu tham khảo
Thummel, 2005, Appendices II. Design and optimization of dosage regimens; Pharmacokinetic data, 1797
Wong, 1996, Effects of divalprox sodium on amitriptyline and nortriptyline pharmacokinetics, Clin Pharmacol Ther, 60, 48, 10.1016/S0009-9236(96)90166-6
Ziegler, 1978, Contribution to the pharmacokinetics of amitriptyline, J Clin Pharmacol, 18, 462, 10.1002/j.1552-4604.1978.tb01572.x
Miyake, 1992, Pharmacokinetic analysis of amitriptyline and its demethylated metabolite in serum and brain ofrats after acute and chronic oral administration of amitriptyline, J Pharmacobiodyn, 15, 157, 10.1248/bpb1978.15.157
Coudore, 1996, Pharmacokinetics of amitriptyline and its demethylated and hydroxylated metabolites in streptozotocin-induced diabetic rats, Gen Pharmacol, 27, 803, 10.1016/0306-3623(95)02082-9
Rutkowska, 1999, Chronopharmacokinetics of amitriptyline in rats, Biopharm Drug Dispos, 20, 117, 10.1002/(SICI)1099-081X(199904)20:3<117::AID-BDD171>3.0.CO;2-V
Baeck, 2000, Blood concentrations of amitriptyline and its metabolite in rats after acute oral administration of amitriptyline, J Anal Toxicol, 24, 271, 10.1093/jat/24.4.271
Murakami, 2003, Separate assessment of intestinal and hepatic first-pass effects using a rat model with double cannulation of the portal and jugular veins, Drug Metab Pharmacokinet, 18, 242, 10.2133/dmpk.18.252
Yu, 2003, Dose-independent pharmacokinetics of a new reversible proton pump inhibitor, KR-60436, after intravenous and oral administration to rats: Gastrointestinal first-pass effect, J Pharm Sci, 92, 1592, 10.1002/jps.10427
Gibaldi, 1982
Ohshima, 1994, Tissue distribution and metabolism ofamitriptyline after repeated administration in rats, Drug Metab Dispos, 22, 21
Lee, 1983, Evaluation of potential causes for the incomplete bioavailability of furosemide: Gastric first-pass metabolism, J Pharmacokinet Biopharm, 11, 623, 10.1007/BF01059061
Mitruka, 1981
Bae, 2004, Pharmacokinetics of DA-7867, a new oxazolidinone, after intravenous or oral administration to rats: Intestinal first-pass effect, Antimicrob Agents Chemother, 48, 659, 10.1128/AAC.48.2.659-662.2004
Bae, 2005, Hepatic and intestinal first-pass effects of oltipraz in rats, Biopharm Drug Dispos, 26, 129, 10.1002/bdd.439
Chung, 2006, Pharmacokinetics of DA-6034, an agent for inflammatory bowel disease, in rats and dogs: Contribution of intestinal first-pass effect to low bioavailability in rats, Eur J Pharm Sci, 27, 363, 10.1016/j.ejps.2005.11.008
Choi, 2006, Dose-independent pharmacokinetics of metformin in rats: Hepatic and gastrointestinal first-pass effects, J Pharm Sci, 95, 2543, 10.1002/jps.20744
Kim, 2002, Pharmacokinetics of ipriflavone, an isoflavone derivative, after intravenous and oral administration to rats: Hepatic and intestinal first-pass effects, Life Sci, 70, 1299, 10.1016/S0024-3205(01)01508-9
Kim, 1998, Hepatic and intestinal first-pass effects of a new hepatoprotective agent, YH439, in rats, Res Commun Mol Pathol Pharmacol, 102, 125