So sánh dược động học của quercetin, isoquercitrin và quercetin-3-O-β-D-glucuronide ở chuột bằng HPLC-MS

Aguirre, 2014, Effects of resveratrol and other polyphenols in hepatic steatosis, World Journal of Gastroenterology, 20, 7366, 10.3748/wjg.v20.i23.7366

Awad, 2000, Peroxidase-catalyzed formation of quercetin quinone methide–glutathione adducts, Archives of Biochemistry & Biophysics, 378, 224, 10.1006/abbi.2000.1832

Boots, 2008, Health effects of quercetin: from antioxidant to nutraceutical, European Journal of Pharmacology, 585, 325, 10.1016/j.ejphar.2008.03.008

Cermak, 2003, The bioavailability of quercetin in pigs depends on the glycoside moiety and on dietary factors, Journal of Nutrition, 133, 2802, 10.1093/jn/133.9.2802

Chang, 2005, Difference in absorption of the two structurally similar flavonoid glycosides, hyperoside and isoquercitrin, in rats, European Journal of Pharmaceutics and Biopharmaceutics, 59, 549, 10.1016/j.ejpb.2004.10.004

Crespy, 1998, Quercetin is recovered in human plasma as conjugated derivatives which retain antioxidant properties, FEBS Letters, 426, 331, 10.1016/S0014-5793(98)00367-6

Crespy, 2002, Quercetin, but not its glycosides, is absorbed from the rat stomach, Journal of Agricultural and Food Chemistry, 50, 618, 10.1021/jf010919h

Day, 2000a, Conjugation position of quercetin glucuronides and effect on biological activity, Free Radical Biology and Medicine, 29, 1234, 10.1016/S0891-5849(00)00416-0

Day, 2000b, Dietary flavonoid and isoflavone glycosides are hydrolysed by the lactase site of lactase phlorizin hydrolase, FEBS Letters, 468, 166, 10.1016/S0014-5793(00)01211-4

Day, 2003, Absorption of quercetin-3-glucoside and quercetin-4′-glucoside in the rat small intestine: the role of lactase phlorizin hydrolase and the sodium-dependent glucose transporter, Biochemical Pharmacology, 65, 1199, 10.1016/S0006-2952(03)00039-X

Ding, 2014, Lipid modulatory activities of Cichorium glandulosum Boiss et Huet are mediated by multiple components within hepatocytes, Scientific Reports, 4, 4715, 10.1038/srep04715

Food and Drug Administration of the United States (FDA), 2013, Guidance for industry bioanalytical method validation

Fraga, 2009, Biochemical Actions of Plant Phenolics Compounds: Thermodynamic and Kinetic Aspects, Plant Phenolics and Human Health: Biochemistry, Nutrition, and Pharmacology, 3, 91, 10.1002/9780470531792

Guo, 2014, Quercetin and quercetin-3-O-glucuronide are equally effective in ameliorating endothelial insulin resistance through inhibition of reactive oxygen species - associated inflammation, Molecular Nutrition & Food Research, 57, 1037, 10.1002/mnfr.201200569

He, 2013, A sensitive LC–MS/MS method for simultaneous determination of six flavonoids in rat plasma: application to a pharmacokinetic study of total flavonoids from mulberry leaves, Journal of Pharmaceutical and Biomedical Analysis, 84, 189, 10.1016/j.jpba.2013.06.019

Huh, 2007, Comparison of oral bioavailability of genistein and genistin in rats, International Journal of Pharmaceutics, 337, 148, 10.1016/j.ijpharm.2006.12.046

Kashiwada, 2005, Anti-HIV benzylisoquinoline alkaloids and flavonoids from the leaves of Nelumbo nucifera, and structure–activity correlations with related alkaloids, Bioorganic & Medicinal Chemistry, 13, 443, 10.1016/j.bmc.2004.10.020

Kawai, 2008, Macrophage as a target of quercetin glucuronides in human atherosclerotic arteries: implication in the anti-atherosclerotic mechanism of dietary flavonoids, Journal of Biological Chemistry, 283, 9424, 10.1074/jbc.M706571200

Kitanov, 1988, Miquelianin and other polyphenols from Hypericum hirsutum, Chemistry of Natural Compounds, 24, 119, 10.1007/BF00597593

Kroon, 2004, How should we assess the effects of exposure to dietary polyphenols in vitro?, American Journal of Clinical Nutrition, 80, 15, 10.1093/ajcn/80.1.15

Lee, 2012, Pharmacokinetics of quercetin absorption from apples and onions in healthy humans, Journal of Agricultural & Food Chemistry, 60, 3874, 10.1021/jf3001857

Lesser, 2004, Bioavailability of quercetin in pigs is influenced by the dietary fat content, Journal of Nutrition, 134, 1508, 10.1093/jn/134.6.1508

Li, 2010, HPLC analysis and pharmacokinetic study of quercitrin and isoquercitrin in rat plasma after administration of Hypericum japonicum thunb. extract, Biomedical Chromatography, 22, 374, 10.1002/bmc.942

Lu, 2013, Identification of isoquercitrin metabolites produced by human intestinal bacteria using UPLC-Q-TOF/MS, Biomedical Chromatography, 27, 509, 10.1002/bmc.2820

Manach, 1997, Bioavailability of rutin and quercetin in rats, FEBS Letters, 409, 12, 10.1016/s0014-5793(97)00467-5

Menendez, 2011, Vascular deconjugation of quercetin glucuronide: the flavonoid paradox revealed?, Molecular Nutrition & Food Research, 55, 1780, 10.1002/mnfr.201100378

Moon, 2001, Identification of quercetin 3-O-β-D-glucuronide as an antioxidative metabolite in rat plasma after oral administration of quercetin, Free Radical Biology and Medicine, 30, 1274, 10.1016/s0891-5849(01)00522-6

Murakami, 2008, Multitargeted cancer prevention by quercetin, Cancer Letters, 269, 315, 10.1016/j.canlet.2008.03.046

Murota, 2010, α-Oligoglucosylation of a sugar moiety enhances the bioavailability of quercetin glucosides in humans, Archives of Biochemistry and Biophysics, 501, 91, 10.1016/j.abb.2010.06.036

Murota, 2000, Efficiency of absorption and metabolic conversion of quercetin and its glucosides in human intestinal cell line Caco-2, Archives of Biochemistry and Biophysics, 384, 391, 10.1006/abbi.2000.2123

Paganga, 1997, The identification of flavonoids as glycosides in human plasma, FEBS Letters, 401, 78, 10.1016/s0014-5793(96)01442-1

Paulke, 2012, Isoquercitrin provides better bioavailability than quercetin: comparison of quercetin metabolites in body tissue and brain sections after six days administration of isoquercitrin and quercetin, Die Pharmazie, 67, 991

Petri, 2003, Absorption/metabolism of sulforaphane and quercetin, and regulation of phase II enzymes, in human jejunum in vivo, Drug Metabolism and Disposition, 31, 805, 10.1124/dmd.31.6.805

Rowland, 2018, Gut microbiota functions: metabolism of nutrients and other food components, European Journal of Nutrition, 57, 1, 10.1007/s00394-017-1445-8

Schoefer, 2003, Anaerobic degradation of flavonoids by Clostridium orbiscindens, Applied and Environmental Microbiology, 69, 5849, 10.1128/aem.69.10.5849-5854.2003

Sesink, 2001, Quercetin glucuronides but not glucosides are present in human plasma after consumption of quercetin-3-glucoside or quercetin-4′-glucoside, Journal of Nutrition, 131, 1938, 10.1093/jn/131.7.1938

Shimoi, 2001, Deglucuronidation of a flavonoid, luteolin monoglucuronide, during inflammation, Drug Metabolism and Disposition: the biological fate of chemicals, 29, 1521

Shirai, 2001, Inhibitory effect of a quercetin metabolite, quercetin 3-O-β-D-glucuronide, on lipid peroxidation in liposomal membranes, Journal of Agricultural and Food Chemistry, 49, 5602, 10.1021/jf010713g

Shirai, 2002, Effect of quercetin and its conjugated metabolite on the hydrogen peroxide-induced intracellular production of reactive oxygen species in mouse fibroblasts, Bioscience, Biotechnology, and Biochemistry, 66, 1015, 10.1271/bbb.66.1015

Spencer, 1999, The small intestine can both absorb and glucuronidate luminal flavonoids, FEBS Letters, 458, 224, 10.1016/S0014-5793(99)01160-6

Sun, 2002, The “French Paradox” and beyond: neuroprotective effects of polyphenols, Free Radical Biology and Medicine, 32, 314, 10.1016/S0891-5849(01)00803-6

Terao, 2009, Dietary flavonoids as antioxidants, Forum of Nutrition, 61, 87, 10.1159/000212741

Terao, 2008, Vegetable flavonoids and cardiovascular disease, Asia Pacific Journal of Clinical Nutrition, 17, 291

Terao, 2011, Conjugated quercetin glucuronides as bioactive metabolites and precursors of aglycone in vivo, Food & Function, 2, 11, 10.1039/c0fo00106f

Vacek, 2012, Biotransformation of flavonols and taxifolin in hepatocyte in vitro systems as determined by liquid chromatography with various stationary phases and electrospray ionization-quadrupole time-of-flight mass spectrometry, Journal of Chromatography B, 899, 109, 10.1016/j.jchromb.2012.05.009

Valentová, 2014, Isoquercitrin: pharmacology, toxicology, and metabolism, Food & Chemical Toxicology, 68, 267, 10.1016/j.fct.2014.03.018

Vrba, 2013, A novel semisynthetic flavonoid 7-O-galloyltaxifolin upregulates heme oxygenase-1 in RAW264.7 cells via MAPK/Nrf2 pathway, Journal of Medicinal Chemistry, 56, 856, 10.1021/jm3013344

Walle, 2004, Absorption and metabolism of flavonoids, Free Radical Biology and Medicine, 36, 829, 10.1016/j.freeradbiomed.2004.01.002

Xing, 2005, Absorption and enterohepatic circulation of baicalin in rats, Life Sciences, 78, 140, 10.1016/j.lfs.2005.04.072

Xue, 2011, Identification of the potential active components of Abelmoschus manihot in rat blood and kidney tissue by microdialysis combined with ultra-performance liquid chromatography/quadrupole time-of-flight mass spectrometry, Journal of Chromatography B, 879, 317, 10.1016/j.jchromb.2010.12.016

Yang, 2016, Pharmacokinetic comparison between quercetin and quercetin 3-O-β-glucuronide in rats by UHPLC-MS/MS, Scientific Reports, 6, 35460, 10.1038/srep35460

Yoshino, 2011, Effect of quercetin and glucuronide metabolites on the monoamine oxidase-A reaction in mouse brain mitochondria, Nutrition, 27, 847, 10.1016/j.nut.2010.09.002

Youdim, 2004, Flavonoids and the brain: interactions at the blood–brain barrier and their physiological effects on the central nervous system, Free Radical Biology and Medicine, 37, 1683, 10.1016/j.freeradbiomed.2004.08.002

Yuan, 2016, Transformation of trollioside and isoquercetin by human intestinal flora in vitro, Chinese Journal of Natural Medicines, 14, 220, 10.1016/s1875-5364(16)30019-x

Zhou, 2011, A sensitive LC–MS–MS method for simultaneous quantification of two structural isomers, hyperoside and isoquercitrin: application to pharmacokinetic studies, Chromatographia, 73, 353, 10.1007/s10337-010-1879-0

Zuo, 2006, Intestinal absorption of hawthorn flavonoids—in vitro, in situ and in vivo correlations, Life Sciences, 79, 2455, 10.1016/j.lfs.2006.08.014