Persistent haematuria and proteinuria due to glomerular disease in related Abyssinian cats

Journal of Feline Medicine and Surgery - Tập 10 - Trang 219-229 - 2008
Joanna D. White1, Jacqueline M. Norris1, Katrina L. Bosward1, R. Fleay2, Chris Lauer3, Richard Malik1,4
1Faculty of Veterinary Science, Building B14, The University of Sydney, NSW 2006, Australia
2Chirnside Park Veterinary Clinic, Chirnside Park, Victoria 3116, Australia
3Symbion Laverty Pathology, North Ryde, NSW 2113, Australia
4Post Graduate Foundation in Veterinary Science, Building B22, The University of Sydney, NSW 2006, Australia

Tóm tắt

Eight cases of glomerular disease in young, related Abyssinian cats are described. Haematuria was the most consistent feature. Six cats developed the nephrotic syndrome. The short-term prognosis was good for cats with haematuria and fair for cats with the nephrotic syndrome as oedema resolved in three of the six cats. Light microscopic examination of renal biopsies from three cats was considered normal or revealed only mild abnormalities. In the three cases subjected to necropsy, histological abnormalities included mild mesangial hypercellularity and adhesions between the glomerular tuft and Bowman's capsule consistent with a focal proliferative glomerulopathy. Further investigation into this glomerulopathy will require ultrastructural and immunohistochemical studies to characterise the glomerular abnormality and genetic analyses to investigate its potential to be an inherited disease. Glomerular disease, potentially a familial one, should be considered in the investigation of persistent haematuria or proteinuria in Abyssinian and related cats.

Tài liệu tham khảo

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Thông tin xuất bản

Journal of Feline Medicine and Surgery

Tập 10

219-229

Thông tin tác giả