Periodontitis in individuals with liver cirrhosis: A case–control study

Journal of Clinical Periodontology - Tập 46 Số 10 - Trang 991-998 - 2019
Fernando Oliveira Costa1, Eugênio José Pereira Lages2, Elizabeth Maria Bastos Lages1, Luís Otávio Miranda Cota1
1Department of Periodontology, School of Dentistry, Federal University of Minas Gerais, Belo Horizonte, Minas Gerais, Brazil
2Department of Dental Clinics, Oral Pathology, and Oral Surgery, School of Dentistry, Federal University of Minas Gerais, Belo Horizonte, Minas Gerais, Brazil

Tóm tắt

AbstractAim

The aim of this study was to evaluate the association between liver cirrhosis and periodontitis.

Methods

This case–control study included 294 individuals, 98 cases with liver cirrhosis and 196 controls. A full‐mouth periodontal examination was performed and plaque index, probing depth, clinical attachment level and bleeding on probing were recorded. The association of risk variables with periodontitis was tested through univariate analysis and multivariate logistic regression, stratified by alcohol status.

Results

A high prevalence of periodontitis was observed among cases (62.2%) when compared to controls (41.8%). Individuals with cirrhosis presented a chance ~2 higher of having periodontitis than controls (OR = 2.28; 95% CI 1.39–3.78; p < .001). Significant variables associated with periodontitis in the final logistic models were as follows: (a) no/occasional alcohol use model—number of teeth up 14, age ≥45–55 years, male sex and smoking; (b) moderate and intensive alcohol use models—cirrhosis, number of teeth up 14, age ≥45–55 years, male sex and smoking.

Conclusions

An important risk association between liver cirrhosis and periodontitis was observed. Additionally, the intensive alcohol use significantly increased the risk for periodontitis.

Từ khóa


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