Perinatal methylmercury intoxication: Behavioral effects in rats

Developmental Psychobiology - Tập 14 Số 3 - Trang 213-219 - 1981
Robert L. Schalock1, Wendy J. Brown2, Ruth Kark3, N.K. Menon3
1Department of Psychology, Hastings College, Hastings, Nebraska 68901, U.S.A.
2Department of Pathology Division of Neuropathology Center for the Health Sciences University of California Los Angeles, California
3Reed Neurological Research Center, UCLA School of Medicine, Los Angeles, California

Tóm tắt

AbstractSprague‐Dawley rats were subjected to perinatal (4th gestational day until Postnatal Day 21) methylmercury intoxication to determine the long‐term behavioral effect of the mercury poisoning. Experimental and control animals were evaluated at 110–140 days of age. Compared to controls, the methylmercury animals demonstrated significant behavioral deficits characterized by hypoactivity and by reduced appetitive, escape, and avoidance learning.

Từ khóa


Tài liệu tham khảo

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10.1037/h0077452

10.1016/0031-9384(77)90223-2

10.1002/dev.420120302

10.1002/dev.420060607

10.1126/science.155.3765.1033

10.1056/NEJM197105062841806

10.1001/archneur.1972.00490100109013

Thông tin
Thông tin xuất bản

Developmental Psychobiology

Tập 14 Số 3

213-219

Thông tin tác giả