Perfluorocarbon Enhancement of Heterologous Red Cell Survival: A Reticuloendothelial Block Effect?

International Archives of Allergy and Immunology - Tập 70 Số 1 - Trang 88-91 - 1983
Oswaldo Castro1, C. A. Reindorf1, W.W. Socha2, Arthur W. Rowe3
1Center for Sickle Cell Disease, Howard University College of Medicine, Washington, D.C.
2Laboratory of Experimental Medicine and Surgery in Primates (LEMSIP), New York University School of Medicine, New York, N.Y.
3The Lindsley F. Kimball Research Institute of The New York Blood Center, New York, N. Y., USA

Tóm tắt

The intravascular survival of human erythrocytes transfused to primate animals was prolonged by infusing the recepients with a perfluorocarbon red cell substitute (Fluosol DA). This effect is probably due to transient block of the animals’ reticuloendothelial system by the perfluorocarbon emulsion. Perfluorocarbon compounds could be used to study the role of reticuloendothelial function in the immune destruction of red cells.

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International Archives of Allergy and Immunology

Tập 70 Số 1

88-91

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