Pediatric Restless Legs Syndrome

Journal of Child Neurology - Tập 26 Số 11 - Trang 1365-1376 - 2011
Daniel L. Picchietti1, Robert Arbuckle2, Linda Abetz2, Jeffrey S. Durmer3, Anna Ivanenko4, Judith Owens5, Jens Croenlein6, Richard P. Allen7, Arthur S. Walters8
1University of Illinois School of Medicine and Carle Foundation Hospital, Urbana, Illinois
2Mapi Values Ltd, Cheshire, United Kingdom
3Georgia State University and Fusion Sleep Medicine Program, Atlanta, Georgia
4Division of Child and Adolescent Psychiatry, Children’s Memorial Hospital, Chicago, Illinois
5Ambulatory Pediatrics, Brown Medical School, Providence, Rhode Island
6Boehringer Ingelheim Pharma GmbH & Co. KG, Clinical Research CNS, Biberach, Germany
7Department of Neurology, Johns Hopkins University, Baltimore, Maryland
8Department of Neurology, Vanderbilt University School of Medicine, Nashville, Tennessee

Tóm tắt

The specific aims of this study were to collect and analyze detailed symptom descriptions from patients with pediatric restless legs syndrome, ages 6 to 17 years, as well as assess symptom impact and the usefulness of drawings. Trained qualitative interviewers conducted face-to-face audio-recorded interviews of children and adolescents who met criteria for definite restless legs syndrome. Thirty-three patients in 3 age groups used 16 different categories of descriptors for restless legs sensations, with a mean of 3 or more categories used per patient in each age group. “Need to move/kick,” “pain/hurts,” “uncomfortable/cannot get comfortable,” and “like bugs or ants/crawling” were the most common descriptors. Two-thirds reported daytime sensations, and nearly half had arm involvement. They described impact on sleep, cognitive function, and affect. Drawings provided useful diagnostic information. These detailed empirical data will be useful in clinical practice, as well as in the development of formal diagnostic tools and severity measures.

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