Paroxysmal Laryngospasm Secondary to Gastroesophageal Reflux

Laryngoscope - Tập 106 Số 12 - Trang 1502-1505 - 1996
Christopher J. Loughlin1, James A. Koufman2
1Center for Voice Disorders of Wake Forest University, Department of Otolaryngology, Bowman Gray School of Medicine, Winston-Salem, NC 27157-1034, USA.
2James A. Koufman, MD, Center For Voice Disorders, Department of Otolaryngology, Bowman Gray School of Medicine, Medical Center Boulevard, Winston‐Salem, NC 27157‐1034.

Tóm tắt

AbstractOver a 2‐year period (1992 to 1994), 12 consecutive adult patients with paroxysmal laryngospasm were prospectively studied. All had had other symptoms of gastroesophageal reflux (GER); however, only 4 (33%) experienced symptoms of heartburn. Each patient underwent fiberoptic laryngeal examination, barium swallow/esophagography, and ambulatory, 24‐hour, double‐probe pH monitoring(pH‐metry).Eleven (92%) of the 12 patients had evidence of GER on examination, and 10(83%) had abnormal pH‐metry, including 3 who demonstrated pharyngeal reflux while having normal total acid exposure times in the esophageal probe. All the patients responded to antireflux treatment, using dietary and lifestyle modifications and omeprazole, with complete cessation of the laryngospastic episodes.This study documents the role of GER in the etiology of paroxysmal laryngospasm, it highlights the advantages of double‐probe pH‐metry in diagnosing this extraesophageal manifestation of GER, and it demonstrates that antireflux therapy with omeprazole is effective in controlling GER‐induced laryngospasm.

Từ khóa


Tài liệu tham khảo

10.1002/lary.1991.101.s53.1

10.1288/00005537-196811000-00007

10.1017/S0022215100075356

10.1288/00005537-198811000-00009

10.1177/019459988809900403

10.1136/gut.30.2.233

10.1288/00005537-197709000-00002

10.1542/peds.85.6.1034

10.1177/000348947708600203

10.1111/j.1445-5994.1990.tb00396.x

10.1213/00000539-197801000-00025

10.1007/BF02408140

10.1177/000348949210100905

10.1378/chest.84.3.301

10.1203/00006450-197910000-00013

10.1288/00005537-199311000-00006

10.1152/jappl.1982.53.2.455

10.1542/peds.55.5.640

10.1288/00005537-199402000-00015

Ott DJ, 1986, The role of diagnostic imaging in evaluating gastroesophageal reflux disease, Postgrad Radiol, 6, 3

10.1097/00004836-198012000-00016

10.1007/BF01300382

Thông tin
Thông tin xuất bản

Laryngoscope

Tập 106 Số 12

1502-1505

Thông tin tác giả