Palladium-catalyzed amination of quinaldine-5-triflate

Central European Journal of Chemistry - Tập 6 - Trang 33-37 - 2008
Melinda Fekete1, Mercedesz Töröncsi1, Lajos Novak1
1Department of Organic Chemistry and Technology, Budapest University of Technology and Economics, Research Group for Alkaloid Chemistry, Hungarian Academy of Sciences, Budapest, Hungary

Tóm tắt

Palladium-catalyzed amination reactions of quinoline triflate and the effect of a Pd catalyst, its ligands, solvents, bases, and temperature were studied. This method facilitated an easier pathway for the preparation of aminoquinoline derivatives as potential precursors of new serotoninerg agents.

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