Pain management after total hip arthroplasty at five different Danish hospitals: A prospective, observational cohort study of 501 patients

Acta Anaesthesiologica Scandinavica - Tập 63 Số 7 - Trang 923-930 - 2019
A. Geisler1,1,2, Jørgen B. Dahl3, Kasper Højgaard Thybo4, Tim H. Pedersen5, M.L.K. Jørgensen6, Dina Hansen7, Louise K. Schulze8, Eva Persson2, Ole Mathiesen9
1Department of Anaesthesiology, Centre of Head and Orthopaedics, Copenhagen University Hospital, Rigshospitalet, Copenhagen, Denmark
2Department of Health Sciences, Faculty of Medicine, Lund University, Lund, Sweden
3Department of Anaesthesiology, Bispebjerg and Frederiksberg University Hospital, Copenhagen, Denmark
4Department of Anaesthesiology, Næstved Hospital, Næstved, Denmark
5Department of Orthopedics, Bispebjerg and Frederiksberg University Hospital, Copenhagen, Denmark
6Department of Orthopedics Zealand University Hospital Køge Denmark
7Department of Orthopedics Nykøbing Falster Hospital Nykøbing Falster Denmark
8Department of Orthopedics Nordsjællands Hospital Hillerød Denmark
9Department of Anaesthesiology, Zealand University Hospital, Køge, Denmark

Tóm tắt

BackgroundThe available literature does not present a “gold standard” for post‐operative pain treatment after total hip arthroplasty (THA). The aim of this prospective observational study was to explore and document post‐operative pain treatment, including outcomes, in a large cohort of patients undergoing THA at five different Danish hospitals.MethodsThis prospective, multicentre, observational cohort study of 501 THA patients was performed at five different hospitals in the Capital Region and at the Region Zealand in Denmark, from April 2014 to April 2016. The study had two co‐primary outcomes: Pain during mobilisation at 6 hours post‐operatively (numeric rating scale [NRS] [0‐10]) and morphine consumption 0‐24 hours post‐operatively.ResultsA large variety of analgesic treatments were used at the included hospitals and none of the hospitals used the same non‐opioid basic analgesic regimen. For all patients at all hospitals, the NRS–pain level during mobilisation at 6 hours was 5 (3‐6), (median [interquartile range]) and the 24‐hour intravenous morphine (eqv) consumption was 25 mg (18‐35). Although some statistically significant differences between hospitals were found for morphine use, no non‐opioid analgesic regimen demonstrated consistent clinically relevant superior efficacy. In general, pain levels at rest were low to moderate and pain during mobilisation was moderate.ConclusionsAnalgesic treatment routines differed between hospitals. Pain levels, however, did not differ substantially and were in general low at rest and moderate during mobilisation. No non‐opioid analgesic treatment demonstrated consistent analgesic superiority.

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Tài liệu tham khảo

10.3109/17453674.2011.618907

10.2106/JBJS.N.01141

10.1080/00016470510030553

10.2106/00004623-200704000-00012

10.1093/bja/aet248

10.1111/j.1365-2044.2005.04382.x

10.1016/j.pain.0000000000000003

10.1016/j.pain.2009.08.007

10.1111/anae.12148

10.1016/j.ijsu.2014.07.013

Kalore VN, 2015, Nerve blocks or no nerve blocks for pain control after elective hip replacement (arthroplasty) surgery in adults, Cochrane Database Syst Rev, 10, 1

10.1111/anae.13179

10.1097/ALN.0b013e31822a24c2

10.1111/aas.12380

10.1111/aas.12815

10.1111/aas.12764

10.1111/aas.12382

10.1185/03007995.2013.860019

Yi MS, 2017, Relationship between the incidence and risk factors of postoperative nausea and vomiting in patients with intravenous patient‐controlled analgesia, Asian J Surg, 1, 1

10.1111/aas.12456

10.1053/apmr.2000.20621

Manchikanti L, 2008, Evidence‐based medicine, systematic reviews, and guidelines in interventional pain management: part 2: randomized controlled trials, Pain Physician, 11, 717, 10.36076/ppj.2008/11/717

10.1097/PRS.0b013e318219c171

10.1136/bmj.312.7040.1215

10.1111/anae.13593