Outcome of cats with diarrhea and Tritrichomonas foetus infection

Journal of the American Veterinary Medical Association - Tập 225 Số 6 - Trang 888-892 - 2004
Derek M. Foster1, Jody L. Gookin, Matthew F. Poore, Marty Stebbins, Michael G. Levy
1Department of Molecular Biomedical Sciences, College of Veterinary Medicine, North Carolina State University, Raleigh, NC 27606, USA

Tóm tắt

AbstractObjective—To determine the long-term outcome of cats infected withTritrichomonas foetusand identify treatment and management strategies influencing resolution of infection or associated diarrhea.Design—Prospective study.Sample Population—26 cats withT foetus-associated diarrhea at least 22 months prior to the study.Procedure—A standardized survey regarding clinical course and management was administered to owners of cats withT foetusinfection and associated diarrhea. Fecal samples were obtained from each cat; the presence ofT foetuswas assessed via microscopic examination of smears, culture in commercial media, and polymerase chain reaction amplification ofT foetusrDNA involving species-specific primers.Results—Survey responses were obtained from owners of all 26 cats. Twenty-three cats had complete resolution of diarrhea a median of 9 months after onset. Analysis of fecal samples obtained from 22 cats revealed persistentT foetusinfection in 12, with a median of 39 months after resolution of diarrhea. History of implementation of a dietary change, treatment with paromomycin, or higher numbers of cats in the household was associated with significantly longer duration of time to resolution of diarrhea.Conclusions and Clinical Relevance—Results suggested chronicT foetus-associated diarrhea in most cats is likely to resolve spontaneously within 2 years of onset. Chronic infection withT foetus(without clinical signs) after resolution of diarrhea appears to be common. Although often temporarily effective in decreasing severity of diarrhea, attempts to treat cats withT foetusinfection may result in prolongation of time to resolution of diarrhea. (J Am Vet Med Assoc2004;225:888–892)

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