Oral supplementation with probiotics in very-low-birth-weight preterm infants: a randomized, double-blind, placebo-controlled trial

Hall, 1990, Factors influencing the presence of faecal lactobacilli in early infancy., Arch Dis Child, 65, 185, 10.1136/adc.65.2.185 Goldmann, 1978, Bacterial colonisation of neonates admitted to an intensive care environment., J Pediatr, 93, 288, 10.1016/S0022-3476(78)80523-X Schwiertz, 2003, Development of the intestinal bacterial composition in hospitalised preterm infants in comparison with breast-fed, full-term infants., Pediatr Res, 54, 393, 10.1203/01.PDR.0000078274.74607.7A Butel, 2007, Conditions of bifidobacterial colonization in preterm infants: a prospective analysis., J Pediatr Gastroenterol Nutr, 44, 577, 10.1097/MPG.0b013e3180406b20 Sakata, 1985, Development of the intestinal flora in very low birth weight infants compared to normal full-term newborns., Eur J Pediatr, 144, 186, 10.1007/BF00451911 Claud, 2001, Hypothesis: inappropriate colonisation of the premature intestine can cause neonatal necrotizing enterocolitis., FASEB J, 15, 1398, 10.1096/fj.00-0833hyp Butel, 1998, Clostridial pathogenicity in experimental necrotizing enterocolitis in gnotobiotic quails and protective role of bifidobacteria., J Med Microbiol, 47, 391, 10.1099/00222615-47-5-391 de la Cochetière, 2004, Early intestinal bacterial colonization and necrotizing enterocolitis in premature infants: the putative role of Clostridium., Pediatr Res, 56, 366, 10.1203/01.PDR.0000134251.45878.D5 Kliegman, 1993, Necrotizing enterocolitis: research agenda for a disease unknown etiology and pathogenesis., Pediatr Res, 34, 701, 10.1203/00006450-199312000-00001 Dai, 1999, Protective nutrients and bacterial colonization in the immature human gut., Adv Pediatr, 46, 353 FAO/WHO. Health and nutrition properties of probiotics in food including powder milk with life lactic acid bacteria. Food and Agriculture Administration of the United Nations and World Health Organization Expert Consultation Report. Available from: http://www.who.int/foodsafety/publications/fs_management/en/probiotics.pdf (cited 18 April 2008). Martin, 2008, Probiotics: role in pathophysiology and prevention in necrotizing enterocolitis., Semin Perinatol, 32, 127, 10.1053/j.semperi.2008.01.006 Deshpande, 2007, Probiotics for prevention of necrotising enterocolitis in preterm neonates with very low birthweight: a systematic review of randomised controlled trials., Lancet, 369, 1614, 10.1016/S0140-6736(07)60748-X Alfaleh, 2008, Probiotics for prevention of necrotizing enterocolitis in preterm infants., Cochrane Database Syst Rev, CD005496 Kitajima, 1997, Early administration ofBifidobacterium breve to preterm neonates: randomised control trial., Arch Dis Child Fetal Neonatal Ed, 76, F101, 10.1136/fn.76.2.F101 Dani, 2002, Probiotics feeding in prevention of urinary tract infection, bacterial sepsis and necrotizing enterocolitis in preterm neonates. A prospective doubleblind study., Biol Neonate, 82, 103, 10.1159/000063096 Costalos, 2003, Enteral feeding of premature neonates with Saccharomyces boulardii., Early Hum Dev, 74, 89, 10.1016/S0378-3782(03)00090-2 Lin, 2005, Oral probiotics reduce the incidence and severity of necrotizing enterocolitis in very low birth weight infants., Pediatrics, 115, 1, 10.1542/peds.2004-1463 Bin-Nun, 2005, Oral probiotics prevent necrotizing enterocolitis in very low birth weight neonates., J Pediatr, 147, 192, 10.1016/j.jpeds.2005.03.054 Manzoni, 2006, Oral supplementation withLactobacillus casei subspecies rhamnosus prevents enteric colonisation by candida species in preterm neonates: a randomised study., Clin Infect Dis, 42, 1735, 10.1086/504324 Mohan, 2006, Effects ofBifidobacterium lactis Bb12 supplementation on intestinal microbiota of preterm neonates: a double placebo controlled, randomised study., J Clin Microbiol, 44, 4025, 10.1128/JCM.00767-06 Reuman, 1986, Lack of effect of Lactobacillus on gastrointestinal bacterial colonization in premature infants., Pediatr Infect Dis, 5, 663, 10.1097/00006454-198611000-00013 Millar, 1993, Enteral feeding of premature infants with Lactobacillus GG., Arch Dis Child, 69, 483, 10.1136/adc.69.5_Spec_No.483 Li, 2004, Effects of bifidobacterium breve supplementation on intestinal flora of low birth weight infants., Pediatr Int, 46, 509, 10.1111/j.1442-200x.2004.01953.x Land, 2005, Lactobacillus sepsis associated with probiotic therapy., Pediatrics, 115, 178, 10.1542/peds.2004-2137 Neu, 2007, Perinatal and neonatal manipulation of the intestinal microbiome: a note of caution., Nutr Rev, 65, 282, 10.1111/j.1753-4887.2007.tb00305.x Whitehead J. The design and analysis of sequential clinical trials. In: Statistics in practice 2nd ed. Chichester, United Kingdom: John Wiley, 1997. Hulot, 2003, Planning and monitoring of placebo-controlled survival trials: comparison of the triangular test with usual interim analyses methods., Br J Clin Pharmacol, 55, 299, 10.1046/j.1365-2125.2003.01768.x Claud EC, Walker WA. The intestinal microbiota and the microbiome. In: Neu J, Polin RA eds. Gastroenterology and nutrition, neonatology questions and controversies. Philadelphia, PA: Saunders, 2008:73–91. Tao, 2006, Soluble factors from Lactobacillus GG activate MAPKs and induce cytoprotective heat shock proteins in intestinal epithelial cells., Am J Physiol Cell Physiol, 290, C1018, 10.1152/ajpcell.00131.2005 Rousseaux, 2007, Lactobacillus acidophilus modulates intestinal pain and induces opioid and cannabinoid receptors., Nat Med, 13, 35, 10.1038/nm1521 Lin, 2008, Oral probiotics prevent necrotizing enterocolitis in very low birth weight preterm infants: a multicenter, randomized, controlled trial., Pediatrics, 122, 693, 10.1542/peds.2007-3007 Canani, 2007, Probiotics for treatment of acute diarrhoea in children: randomised clinical trial of five different preparations., BMJ, 335, 340, 10.1136/bmj.39272.581736.55 Agarwal, 2003, Effects of oral Lactobacillus GG on enteric microflora in low-birth-weight neonates., J Pediatr Gastroenterol Nutr, 36, 397, 10.1097/00005176-200303000-00019 Stansbridge, 1993, Effects of feeding premature infants with Lactobacillus GG on gut fermentation., Arch Dis Child, 69, 488, 10.1136/adc.69.5_Spec_No.488