Tổng hợp một bước các nanoconjugate ZnS lượng tử hòa tan trong nước biocompatible/chitosan

Nanoscale Research Letters - Tập 8 - Trang 1-13 - 2013
Fábio P Ramanery1, Alexandra AP Mansur1, Herman S Mansur1
1Center of Nanoscience, Nanotechnology and Innovation - CeNano2I, Department of Metallurgical and Materials Engineering, Escola de Engenharia, Federal University of Minas Gerais, Minas Gerais, Brazil

Tóm tắt

Chấm lượng tử (QDs) là những tinh thể nano bán dẫn phát quang với tiềm năng lớn trong các ứng dụng y sinh và môi trường. Tuy nhiên, việc loại bỏ khả năng gây độc tế bào tiềm ẩn của QDs được làm từ kim loại nặng vẫn là thách thức đối với cộng đồng nghiên cứu. Do đó, mục tiêu của công trình này là phát triển một phương pháp đơn giản mới để tổng hợp QDs thân thiện với sinh học bằng cách sử dụng các ligand carbohydrate trong hóa học keo nước với các thuộc tính quang học được điều chỉnh bởi pH. Việc tổng hợp QDs ZnS được bao bọc bằng chitosan được thực hiện thông qua quy trình keo nước một bước ở nhiệt độ phòng. Các nanobioconjugate đã được đặc trưng hóa một cách sâu rộng bằng nhiều kỹ thuật khác nhau, và kết quả cho thấy kích thước trung bình của các tinh thể nano ZnS và các đặc tính phát quang của chúng bị ảnh hưởng bởi pH trong quá trình tổng hợp. Vì vậy, các hệ thống biofunctionalized 'không chứa cadmium' mới dựa trên QDs ZnS được bao bọc bằng chitosan đã được phát triển thành công, thể hiện hoạt động phát quang có thể được sử dụng trong một số ứng dụng có thể, chẳng hạn như các đầu dò trong sinh học, y học và dược phẩm.

Từ khóa

#chấm lượng tử #ZnS #nanoconjugate #chitosan #sinh học #y sinh

Tài liệu tham khảo

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