Nutrition and brain development in early life

Nutrition Reviews - Tập 72 Số 4 - Trang 267-284 - 2014
Elizabeth L. Prado1,2, Kathryn G. Dewey1,2
1Department of Nutrition, University of California at Davis, Davis, CA, USA
2Summit Institute of Development, Mataram, Nusa Tenggara Barat, Indonesia

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Tài liệu tham khảo

Black, 2013, Maternal and child undernutrition and overweight in low-income and middle-income countries, Lancet., 382, 427, 10.1016/S0140-6736(13)60937-X

Couperus, 2006, The Blackwell Handbook of Early Childhood Development, 85, 10.1002/9780470757703.ch5

Johnson, 2001, Functional brain development in humans, Nat Rev Neurosci., 2, 475, 10.1038/35081509

Sampaio, 2001, Handbook of Developmental Cognitive Neuroscience, 35

Oppenheim, 1991, Cell death during development of the nervous system, Annu Rev Neurosci., 14, 453, 10.1146/annurev.ne.14.030191.002321

Fugelstad, 2008, Handbook of Developmental Cognitive Neuroscience, 623

Tolsa, 2004, Early alteration of structural and functional brain development in premature infants born with intrauterine growth restriction, Pediatr Res., 56, 132, 10.1203/01.PDR.0000128983.54614.7E

Winick, 1969, The effect of severe early malnutrition on cellular growth of human brain, Pediatr Res., 3, 181, 10.1203/00006450-196903000-00010

Cordero, 1993, Dendritic development in neocortex of infants with early postnatal life undernutrition, Pediatr Neurol., 9, 457, 10.1016/0887-8994(93)90025-8

Cordero, 2003, Dendritic morphology and orientation of pyramidal cells of the neocortex in two groups of early postnatal undernourished-rehabilitated rats, Brain Res Dev Brain Res., 142, 37, 10.1016/S0165-3806(03)00013-0

Jones, 1981, The influence of protein restriction, rehabilitation and changing nutritional status on synaptic development: a quantitative study in rat brain, Brain Res, 208, 97, 10.1016/0006-8993(81)90623-5

Wiggins, 1984, Undernutrition and the development of brain neurotransmitter systems, Life Sciences., 35, 2085, 10.1016/0024-3205(84)90507-1

Hulshoff, 2000, Prenatal exposure to famine and brain morphology in schizophrenia, Am J Psychiatry., 157, 1170, 10.1176/appi.ajp.157.7.1170

Antonow-Schlorke, 2011, Vulnerability of the fetal primate brain to moderate reduction in maternal global nutrient availability, Proc Natl Acad Sci U S A., 108, 3011, 10.1073/pnas.1009838108

Coti Bertrand, 2006, Maternal dietary (n-3) fatty acid deficiency alters neurogenesis in the embryonic rat brain, J Nutr., 136, 1570, 10.1093/jn/136.6.1570

Uauy, 2006, Nutrition in brain development and aging: role of essential fatty acids, Nutr Rev., 64, S24, 10.1301/nr.2006.may.S24-S33

Miller, 1984, Effect of essential fatty acid deficiency on myelin proteins, Lipids., 19, 478, 10.1007/BF02537414

McKenna, 1979, Effect of pre- and postnatal essential fatty acid deficiency on brain development and myelination, J Nutr., 109, 1195, 10.1093/jn/109.7.1195

Rao, 2011, Fetal and neonatal iron deficiency causes volume loss and alters the neurochemical profile of the adult rat hippocampus, Nutr Neurosci., 14, 59, 10.1179/1476830511Y.0000000001

Jorgenson, 2003, Perinatal iron deficiency alters apical dendritic growth in hippocampal CA1 pyramidal neurons, Dev Neurosci., 25, 412, 10.1159/000075667

Jorgenson, 2005, Fetal iron deficiency disrupts the maturation of synaptic function and efficacy in area CA1 of the developing rat hippocampus, Hippocampus., 15, 1094, 10.1002/hipo.20128

Beard, 2003, Iron status and neural functioning, Annu Rev Nutr., 23, 41, 10.1146/annurev.nutr.23.020102.075739

Beard, 2007, Recent evidence from human and animal studies regarding iron status and infant development, J Nutr., 137, 524S, 10.1093/jn/137.2.524S

Kwik-Uribe, 2000, Chronic marginal iron intakes during early development in mice result in persistent changes in dopamine metabolism and myelin composition, J Nutr., 130, 2821, 10.1093/jn/130.11.2821

Escobar, 2007, Iodine deficiency and brain development in the first half of pregnancy, Public Health Nutr., 10, 1554, 10.1017/S1368980007360928

Chen, 1986, Iodine Deficiency Diseases and Congenital Hypothyroidism, 46

Dussault, 1987, Thyroid hormones and brain development, Annu Rev Physiol., 49, 321, 10.1146/annurev.ph.49.030187.001541

Jia-Liu, 1984, Morphologic study on cerebral cortex development in therapeutically aborted fetuses in an endemic goiter region in Guizhou, Chin Med J (Engl)., 97, 67

Sandstead, 1985, W.O. Atwater memorial lecture. Zinc: essentiality for brain development and function, Nutr Rev., 43, 129, 10.1111/j.1753-4887.1985.tb06889.x

Walsh, 1994, Zinc: health effects and research priorities for the 1990s, Environ Health Perspect., 2, 5, 10.1289/ehp.941025

McNall, 1995, The impaired growth induced by zinc deficiency in rats is associated with decreased expression of the hepatic insulin-like growth factor I and growth hormone receptor genes, J Nutr., 125, 874

Blusztajn, 1998, Imprinting of hippocampal metabolism of choline by its availability during gestation: implications for cholinergic neurotransmission, J Physiol Paris., 92, 199, 10.1016/S0928-4257(98)80010-7

Molloy, 2009, Maternal vitamin B12 status and risk of neural tube defects in a population with high neural tube defect prevalence and no folic acid fortification, Pediatrics., 123, 917, 10.1542/peds.2008-1173

Chang, 1981, Effects of vitamin B6 deficiency on morphological changes in dendritic trees in Purkinje cells in developing cerebellum in rats, J Nutr., 111, 848, 10.1093/jn/111.5.848

Groziak, 1990, Effects of maternal restriction of vitamin B6 on neocortex development in rats: neuron differentiation and synaptogenesis, J Nutr., 120, 485, 10.1093/jn/120.5.485

Guilarte, 1993, Vitamin B6 and cognitive development: recent research findings from human and animal studies, Nutr Rev., 51, 193, 10.1111/j.1753-4887.1993.tb03102.x

Guilarte, 1987, Effects of perinatal vitamin B6 deficiency on dopaminergic neurochemistry, J Neurochem., 48, 432, 10.1111/j.1471-4159.1987.tb04111.x

Moore, 1978, Effects of vitamin B6 deficiency on the developing central nervous system of the rat. Myelination, J Nutr., 108, 1260, 10.1093/jn/108.8.1260

Kolb, 1998, Brain plasticity and behavior, Annu Rev Psychol., 49, 43, 10.1146/annurev.psych.49.1.43

Jacobs, 1993, A quantitative dendritic analysis of Wernicke's area in humans. II. Gender, hemispheric, and environmental factors, J Comp Neurol., 327, 97, 10.1002/cne.903270108

Greenough, 1992, Developmental Behavioral Neuroscience, 155

Eluvathingal, 2006, Abnormal brain connectivity in children after early severe socioemotional deprivation: a diffusion tensor imaging study, Pediatrics., 117, 2093, 10.1542/peds.2005-1727

Bengtsson, 2005, Extensive piano practicing has regionally specific effects on white matter development, Nat Neurosci., 8, 1148, 10.1038/nn1516

Juraska, 1988, Sex and environmental influences on the size and ultrastructure of the rat corpus callosum, Brain Res., 450, 1, 10.1016/0006-8993(88)91538-7

Sanchez, 1998, Differential rearing affects corpus callosum size and cognitive function of rhesus monkeys, Brain Res., 812, 38, 10.1016/S0006-8993(98)00857-9

Workman, 2013, Modeling transformations of neurodevelopmental sequences across mammalian species, J Neurosci., 33, 7368, 10.1523/JNEUROSCI.5746-12.2013

Woollett, 2011, Acquiring “the Knowledge” of London's layout drives structural brain changes, Curr Biol., 21, 2109, 10.1016/j.cub.2011.11.018

Nelson, 2007, A neurobiological perspective on early human deprivation, Child Dev Perspect., 1, 13, 10.1111/j.1750-8606.2007.00004.x

Grantham-McGregor, 1991, Nutritional supplementation, psychosocial stimulation, and mental development of stunted children: the Jamaican Study, Lancet., 338, 1, 10.1016/0140-6736(91)90001-6

Waber, 1981, Nutritional supplementation, maternal education, and cognitive development of infants at risk of malnutrition, Am J Clin Nutr., 34, 807, 10.1093/ajcn/34.4.807

Lozoff, 2006, Double burden of iron deficiency in infancy and low socioeconomic status: a longitudinal analysis of cognitive test scores to age 19 years, Arch Pediatr Adolesc Med., 160, 1108, 10.1001/archpedi.160.11.1108

Torche, 2011, The effect of birthweight on childhood cognitive development in a middle-income country, Int J Epidemiol., 40, 1008, 10.1093/ije/dyr030

Watanabe, 2005, Early childhood development interventions and cognitive development of young children in rural Vietnam, J Nutr., 135, 1918, 10.1093/jn/135.8.1918

Pollitt, 1993, Early supplementary feeding and cognition: effects over two decades, Monogr Soc Res Child Dev., 58, 1, 10.2307/1166162

Lozoff, 2010, Home intervention improves cognitive and social-emotional scores in iron-deficient anemic infants, Pediatrics., 126, e884, 10.1542/peds.2009-3535

Gardner, 2005, Zinc supplementation and psychosocial stimulation: effects on the development of undernourished Jamaican children, Am J Clin Nutr., 82, 399, 10.1093/ajcn/82.2.399

Glenn, 2007, Prenatal choline availability modulates hippocampal neurogenesis and neurogenic responses to enriching experiences in adult female rats, Eur J Neurosci., 25, 2473, 10.1111/j.1460-9568.2007.05505.x

Levitsky, 1972, Nutrition and environmental interactions in the behavioural development of the rat: long-term effects, Science., 176, 68, 10.1126/science.176.4030.68

Prado EL Dewey KG Nutrition and brain development in early life 2012

Lozoff, 1998, Behavior of infants with iron-deficiency anemia, Child Dev., 69, 25, 10.1111/j.1467-8624.1998.tb06130.x

Corapci, 2006, Iron deficiency in infancy and mother-child interaction at 5 years, J Dev Behav Pediatr., 27, 371, 10.1097/00004703-200610000-00001

Meeks-Gardner, 1995, Activity and behavioral development in stunted and nonstunted children and response to nutritional supplemenation, Child Dev., 66, 1785, 10.2307/1131910

Moore, 1995, Time course of axonal myelination in the human brainstem auditory pathway, Hear Res., 87, 21, 10.1016/0378-5955(95)00073-D

Kerr, 2011, Model-based analysis and quantification of age trends in auditory evoked potentials, Clin Neurophysiol., 122, 134, 10.1016/j.clinph.2010.05.030

Unay, 2004, Nutritional effects on auditory brainstem maturation in healthy term infants, Arch Dis Child Fetal Neonatal Ed., 89, F177, 10.1136/adc.2002.021014

Georgieff, 2007, Nutrition and the developing brain: nutrient priorities and measurement, Am J Clin Nutr., 85, 614S

Wachs, 2013, Issues in the timing of integrated early interventions: contributions from nutrition, neuroscience and psychological research, Ann N Y Acad Sci.

Morrison, 2008, Sheep models of intrauterine growth restriction: fetal adaptations and consequences, Clin Exp Pharmacol Physiol., 35, 730, 10.1111/j.1440-1681.2008.04975.x

O'Brien, 2003, Maternal iron status influences iron transfer to the fetus during the third trimester of pregnancy, Am J Clin Nutr., 77, 924, 10.1093/ajcn/77.4.924

Tofail, 2008, Effects of prenatal food and micronutrient supplementation on infant development: a randomized trial from the Maternal and Infant Nutrition Interventions, Matlab (MINIMat) study, Am J Clin Nutr, 87, 704, 10.1093/ajcn/87.3.704

Prado, 2012, Maternal multiple micronutrient supplements and child cognition: a randomized trial in Indonesia, Pediatrics., 130, e536, 10.1542/peds.2012-0412

Lozoff, 2012, Iron-fortified vs low-iron infant formula: developmental outcome at 10 years, Arch Pediatr Adolesc Med., 166, 208, 10.1001/archpediatrics.2011.197

Kolb, 2001, Handbook of Developmental Neuroscience, 175

Winick, 1975, Malnutrition and environmental enrichment by early adoption, Science., 190, 1173, 10.1126/science.1198103

Lien, 1977, Early malnutrition and “late” adoption: a study of their effects on the development of Korean orphans adopted into American families, Am J Clin Nutr., 30, 1734, 10.1093/ajcn/30.10.1734

Stein, 1975, Famine and Human Development: The Dutch Hunger Winter of 1944/45

Susser, 1998, Neurodevelopmental disorders after prenatal famine: the story of the Dutch famine study, Am J Epidemiol., 147, 213, 10.1093/oxfordjournals.aje.a009439

Neugebauer, 1999, Prenatal exposure to wartime famine and development of antisocial personality disorder in early adulthood, JAMA., 282, 455, 10.1001/jama.282.5.455

Franzek, 2008, Prenatal exposure to the 1944-45 Dutch “hunger winter” and addiction later in life, Addiction., 103, 433, 10.1111/j.1360-0443.2007.02084.x

Crookston, 2010, Children who recover from early stunting and children who are not stunted demonstrate similar levels of cognition, J Nutr., 140, 1996, 10.3945/jn.109.118927

Engle, 2011, Strategies for reducing inequalities and improving developmental outcomes for young children in low-income and middle-income countries, Lancet., 378, 1339, 10.1016/S0140-6736(11)60889-1

Ashworth, 2003, Guidelines for the Inpatient Treatment of Severely Malnourished Children

Hughes, 2003, The assessment of cognitive performance in children: considerations for detecting nutritional influences, Nutr Rev., 61, 413, 10.1301/nr.2003.dec.413-422

Isaacs, 2008, Nutrition and cognition: assessing cognitive abilities in children and young people, Eur J Nutr., 47, 4, 10.1007/s00394-008-3002-y

Colombo, 2013, Long-term effects of LCPUFA supplementation on childhood cognitive outcomes, Am J Clin Nutr., 98, 403, 10.3945/ajcn.112.040766

Greenfield, 1997, You can't take it with you: why ability assessments don't cross cultures, Am Psychol., 52, 1115, 10.1037/0003-066X.52.10.1115

Vierhaus, 2011, The development of 3- to 9-month-old infants in two cultural contexts: Bayley longitudinal results for Cameroonian and German infants, Eur J Dev Psychol., 8, 349, 10.1080/17405629.2010.505392

Fattal, 2011, The crucial role of thiamine in the development of syntax and lexical retrieval: a study of infantile thiamine deficiency, Brain., 134, 1720, 10.1093/brain/awr068

Grantham-McGregor, 1995, A review of studies of the effect of severe malnutrition on mental development, J Nutr., 125, 2233S, 10.1093/jn/125.suppl_8.2233S

Galler, 2012, Infant malnutrition is associated with persisting attention deficits in middle adulthood, J Nutr., 142, 788, 10.3945/jn.111.145441

Galler, 2012, Socioeconomic outcomes in adults malnourished in the first year of life: a 40-year study, Pediatrics., 130, e1, 10.1542/peds.2012-0073

Grantham-McGregor, 2005, Review of evidence linking protein and energy to mental development, Public Health Nutr., 8, 1191, 10.1079/PHN2005805

Lundgren, 2008, Effects of being born small for gestational age on long-term intellectual performance, Best Pract Res Clin Endocrinol Metab., 22, 477, 10.1016/j.beem.2008.01.014

Walker, 2011, Inequality in early childhood: risk and protective factors for early child development, Lancet., 378, 1325, 10.1016/S0140-6736(11)60555-2

Wang, 2008, Low birth weight, prematurity, and paternal social status: impact on the basic competence test in Taiwanese adolescents, J Pediatr., 153, 333, 10.1016/j.jpeds.2008.04.017

Walker, 2010, The effect of psychosocial stimulation on cognition and behaviour at 6 years in a cohort of term, low-birthweight Jamaican children, Dev Med Child Neurol., 52, e148, 10.1111/j.1469-8749.2010.03637.x

Emond, 2006, Development and behaviour of low-birthweight term infants at 8 years in northeast Brazil: a longitudinal study, Acta Paediatr., 95, 1249, 10.1080/08035250600615127

Sabet, 2009, Low birthweight and subsequent emotional and behavioural outcomes in 12-year-old children in Soweto, South Africa: findings from Birth to Twenty, Int J Epidemiol., 38, 944, 10.1093/ije/dyp204

Strauss, 1998, Growth and development of term children born with low birth weight: effects of genetic and environmental factors, J Pediatr., 133, 67, 10.1016/S0022-3476(98)70180-5

Fattal-Valevski, 1999, Neurodevelopmental outcome in children with intrauterine growth retardation: a 3-year follow-up, J Child Neurol., 14, 724, 10.1177/088307389901401107

Li, 2003, Effects of early childhood supplementation on the educational achievement of women, Pediatrics., 112, 1156, 10.1542/peds.112.5.1156

Hoddinott, 2008, Effect of a nutrition intervention during early childhood on economic productivity in Guatemalan adults, Lancet., 371, 411, 10.1016/S0140-6736(08)60205-6

Rush, 1984, Human Nutrition: A Comprehensive Treatise, 119

Joos, 1983, The Bacon Chow study: maternal nutritional supplementation and infant behavioral development, Child Dev., 54, 669, 10.2307/1130054

Hsueh, 1981, Maternal dietary supplementation and 5 year old Stanford Binet IQ test on the offspring in Taiwan, Fed Proc., 40, 897

Super CM Herrera MG Cognitive outcomes of early nutritional intervention in the Bogota study 1991

Husaini, 1991, Developmental effects of short-term supplementary feeding in nutritionally at-risk Indonesian infants, Am J Clin Nutr., 54, 799, 10.1093/ajcn/54.5.799

Pollitt, 1997, Three-month nutritional supplementation in Indonesian infants and toddlers benefits memory function 8 y later, Am J Clin Nutr, 66, 1357, 10.1093/ajcn/66.6.1357

Pollitt, 2000, Effects of an energy and micronutrient supplement on mental development and behavior under natural conditions in undernourished children in Indonesia, Eur J Clin Nutr., 54, S80, 10.1038/sj.ejcn.1601009

Aitchison, 2000, Effects of an energy and micronutrient supplement on growth and activity, correcting for non-supplemental sources of energy input in undernourished children in Indonesia, Eur J Clin Nutr., 54, S69, 10.1038/sj.ejcn.1601007

Grantham-McGregor, 1997, Effects of early childhood supplementation with and without stimulation on later development in stunted Jamaican children, Am J Clin Nutr., 66, 247, 10.1093/ajcn/66.2.247

Walker, 2000, Effects of stunting in early childhood on growth, IQ and cognition at age 11-12 years and the benefits of nutritional supplementation and psychological stimulation, J Pediatr., 137, 36, 10.1067/mpd.2000.106227

Walker, 2005, Effects of early childhood psychosocial stimulation and nutritional supplementation on cognition and education in growth-stunted Jamaican children: prospective cohort study, Lancet., 366, 1804, 10.1016/S0140-6736(05)67574-5

Walker, 2007, Early childhood stunting is associated with poor psychological functioning in late adolescence and effects are reduced by psychosocial stimulation, J Nutr., 137, 2464, 10.1093/jn/137.11.2464

Innis, 1992, Human milk and formula fatty acids, J Pediatr., 120, S56, 10.1016/S0022-3476(05)81237-5

Kunz, 2000, Oligosaccharides in human milk: structural, functional, and metabolic aspects, Annu Rev Nutr., 20, 699, 10.1146/annurev.nutr.20.1.699

Zeisel, 2000, Choline: needed for normal development of memory, J Am Coll Nutr., 19, 528S, 10.1080/07315724.2000.10718976

Reynolds, 2001, Breastfeeding and brain development, Pediatr Clin North Am., 48, 159, 10.1016/S0031-3955(05)70291-1

Jain, 2002, How good is the evidence linking breastfeeding and intelligence?, Pediatrics., 109, 1044, 10.1542/peds.109.6.1044

Anderson, 1999, Breast-feeding and cognitive development: a meta-analysis, Am J Clin Nutr., 70, 525, 10.1093/ajcn/70.4.525

Drane, 2000, A critical evaluation of the evidence on the association between type of infant feeding and cognitive development, Paediatr Perinat Epidemiol., 14, 349, 10.1046/j.1365-3016.2000.00301.x

Walfisch, 2013, Breast milk and cognitive development - the role of confounders: a systematic review, BMJ Open., 3, e003259, 10.1136/bmjopen-2013-003259

Der, 2006, Effect of breast feeding on intelligence in children: prospective study, sibling pairs analysis, and meta-analysis, BMJ., 333, 945, 10.1136/bmj.38978.699583.55

Ip, 2007, Breastfeeding and maternal and infant health outcomes in developed countries, Evid Rep Technol Assess (Summ), 153, 1

Daniels, 2005, Breast-feeding influences cognitive development in Filipino children, J Nutr., 135, 2589, 10.1093/jn/135.11.2589

Victora, 2005, Breastfeeding and school achievement in Brazilian adolescents, Acta Paediatr., 94, 1656, 10.1080/08035250500252658

Brion, 2011, What are the causal effects of breastfeeding on IQ, obesity and blood pressure? Evidence from comparing high-income with middle-income cohorts, Int J Epidemiol., 40, 670, 10.1093/ije/dyr020

Kramer, 2008, Breastfeeding and child cognitive development: new evidence from a large randomized trial, Arch Gen Psychiatry., 65, 578, 10.1001/archpsyc.65.5.578

Makrides, 2011, Impact of fatty acid status on growth and neurobehavioural development in humans, Matern Child Nutr., 7, 80, 10.1111/j.1740-8709.2011.00304.x

Qawasmi, 2012, Meta-analysis of long-chain polyunsaturated fatty acid supplementation of formula and infant cognition, Pediatrics., 129, 1141, 10.1542/peds.2011-2127

Martinez, 1991, Developmental profiles of polyunsaturated fatty acids in the brain of normal infants and patients with peroxisomal diseases: severe deficiency of docosahexaenoic acid in Zellweger's and pseudo-Zellweger's syndromes, World Rev Nutr Diet., 66, 87, 10.1159/000419282

Adu-Afarwuah, 2007, Randomized comparison of 3 types of micronutrient supplements for home fortification of complementary foods in Ghana: effects on growth and motor development, Am J Clin Nutr., 86, 412, 10.1093/ajcn/86.2.412

Wang, 2006, Effects of nutrient fortified complementary food supplements on development of infants and young children in poor rural area of Gansu Province, Wei Sheng Yan Jiu., 35, 772

Merwe, 2013, Long-chain PUFA supplementation in rural African infants: a randomized controlled trial of effects on gut integrity, growth, and cognitive development, Am J Clin Nutr., 97, 45, 10.3945/ajcn.112.042267

Phuka, 2012, Developmental outcomes among 18-month-old Malawians after a year of complementary feeding with lipid-based nutrient supplements or corn-soy flour, Matern Child Nutr., 8, 239, 10.1111/j.1740-8709.2011.00294.x

Gould, 2013, The effect of maternal omega-3 (n-3) LCPUFA supplementation during pregnancy on early childhood cognitive and visual development: a systematic review and meta-analysis of randomized controlled trials, Am J Clin Nutr., 97, 531, 10.3945/ajcn.112.045781

World Health Organization, Centers for Disease Control and Prevention, 2008, Worldwide Prevalence of Anaemia 1993-2005. WHO Global Database on Anaemia

Brown, 2004, International Zinc Nutrition Consultative Group (IZiNCG) technical document #1. Assessment of the risk of zinc deficiency in populations and options for its control, Food Nutr Bull., 25, S99

Benoist, 2008, Iodine deficiency in 2007: global progress since 2003, Food Nutr Bull., 29, 195, 10.1177/156482650802900305

Lozoff, 2006, Long-lasting neural and behavioral effects of iron deficiency in infancy, Nutr Rev., 64, S34, 10.1301/nr.2006.may.S34-S43

Walker, 2007, Child development: risk factors for adverse outcomes in developing countries, Lancet., 369, 145, 10.1016/S0140-6736(07)60076-2

Christian, 2010, Prenatal micronutrient supplementation and intellectual and motor function in early school-aged children in Nepal, JAMA., 304, 2716, 10.1001/jama.2010.1861

Li, 2009, Effects of maternal micronutrient supplementation on the mental development of infants in rural western China: follow-up evaluation of a double-blind, randomized, controlled trial, Pediatrics., 123, e685, 10.1542/peds.2008-3007

Zhou, 2006, Effect of iron supplementation during pregnancy on the intelligence quotient and behavior of children at 4 y of age: long-term follow-up of a randomized controlled trial, Am J Clin Nutr., 83, 1112, 10.1093/ajcn/83.5.1112

Berglund, 2013, Effects of iron supplementation of LBW infants on cognition and behavior at 3 years, Pediatrics., 131, 47, 10.1542/peds.2012-0989

Christian, 2011, Preschool iron-folic acid and zinc supplementation in children exposed to iron-folic acid in utero confers no added cognitive benefit in early school-age, J Nutr., 141, 2042, 10.3945/jn.111.146480

Murray-Kolb, 2012, Preschool micronutrient supplementation effects on intellectual and motor function in school-aged Nepalese children, Arch Pediatr Adolesc Med., 166, 404, 10.1001/archpediatrics.2012.37

World Health Organization, 2011, Guideline: Use of Multiple Micronutrient Powders for Home Fortification of Foods Consumed by Infants and Children 6-23 Months of Age

Dewey, 2007, Session 4: mineral metabolism and body composition iron status of breast-fed infants, Proc Nutr Soc., 66, 412, 10.1017/S002966510700568X

Black, 2011, Iron deficiency and iron-deficiency anemia in the first two years of life: strategies to prevent loss of developmental potential, Nutr Rev., 69, S64, 10.1111/j.1753-4887.2011.00435.x

Pharoah, 1971, Neurological damage to the fetus resulting from severe iodine deficiency during pregnancy, Lancet., 1, 308, 10.1016/S0140-6736(71)91040-3

Bleichrodt, 1994, The Damaged Brain of Iodine Deficiency, 195

Qian, 2005, The effects of iodine on intelligence in children: a meta-analysis of studies conducted in China, Asia Pac J Clin Nutr., 14, 32

Melse-Boonstra, 2010, Iodine deficiency in pregnancy, infancy and childhood and its consequences for brain development, Best Pract Res Clin Endocrinol Metab., 24, 29, 10.1016/j.beem.2009.09.002

O'Donnell, 2002, Effects of iodine supplementation during pregnancy on child growth and development at school age, Dev Med Child Neurol., 44, 76, 10.1017/S0012162201001712

Bath, 2013, Effect of inadequate iodine status in UK pregnant women on cognitive outcomes in their children: results from the Avon Longitudinal Study of Parents and Children (ALSPAC), Lancet., 382, 331, 10.1016/S0140-6736(13)60436-5

Bougma, 2013, Iodine and mental development of children 5 years old and under: a systematic review and meta-analysis, Nutrients., 5, 1384, 10.3390/nu5041384

Sandstead, 2000, History of zinc as related to brain function, J Nutr., 130, 496S, 10.1093/jn/130.2.496S

Golub, 1995, Developmental zinc deficiency and behavior, J Nutr., 125, 2263S, 10.1093/jn/125.suppl_8.2263S

Caulfield, 2010, Maternal gestational zinc supplementation does not influence multiple aspects of child development at 54 mo of age in Peru, Am J Clin Nutr., 92, 130, 10.3945/ajcn.2010.29407

Tamura, 2005, Folate status of mothers during pregnancy and mental and psychomotor development of their children at five years of age, Pediatrics., 116, 703, 10.1542/peds.2004-2189

Hamadani, 2002, Zinc supplementation during pregnancy and effects on mental development and behavior of infants: a follow up study, Lancet., 360, 290, 10.1016/S0140-6736(02)09551-X

Lind, 2004, A community-based randomized controlled trial of iron and zinc supplementation in Indonesian infants: effects on growth and development, Am J Clin Nutr., 80, 729, 10.1093/ajcn/80.3.729

Black, 2004, Iron and zinc supplementation promote motor development and exploratory behavior among Bangladesh infants, Am J Clin Nutr., 80, 903, 10.1093/ajcn/80.4.903

Katz, 2010, Daily supplementation with iron plus folic acid, zinc, and their combination is not associated with younger age at first walking unassisted in malnourished preschool children from a deficient population in rural Nepal, J Nutr., 140, 1317, 10.3945/jn.109.119925

Hamadani, 2001, Randomized controlled trial of the effect of zinc supplementation on the mental development of Bangladeshi infants, Am J Clin Nutr., 74, 381, 10.1093/ajcn/74.3.381

Friel, 1993, Zinc supplementation in very-low-birth-weight infants, J Pediatr Gastroenterol Nutr., 17, 97, 10.1097/00005176-199307000-00015

Castillo-Duran, 2001, Effect of zinc supplementation on development and growth of Chilean infants, J Pediatr., 138, 229, 10.1067/mpd.2001.110530

Sazawal, 1996, Effect of zinc supplementation on observed activity in low socioeconomic Indian preschool children, Pediatrics., 98, 1132, 10.1542/peds.98.6.1132

Bentley, 1997, Zinc supplementation affects the activity patterns of rural Guatemalan infants, J Nutr., 127, 1333, 10.1093/jn/127.7.1333

Brown, 2009, Preventive zinc supplementation among infants, preschoolers, and older prepubertal children, Food Nutr Bull., 30, S12, 10.1177/15648265090301S103

Butterworth, 2003, Thiamin deficiency and brain disorders, Nutr Res Rev., 16, 277, 10.1079/NRR200367

Khounnorath, 2011, Clinically unapparent infantile thiamin deficiency in Vientiane, Laos, PLoS Negl Trop Dis., 5, e969, 10.1371/journal.pntd.0000969

Kirksey, 1994, Relation of maternal zinc nutriture to pregnancy outcome and infant development in an Egyptian village, Am J Clin Nutr., 60, 782, 10.1093/ajcn/60.5.782

Rahmanifar, 1993, Diet during lactation associated with infant behavior and caregiver-infant interaction in a semirural Egyptian village, J Nutr., 123, 164

Strand, 2013, Cobalamin and folate status predicts mental development scores in North Indian children 12-18 mo of age, Am J Clin Nutr., 97, 310, 10.3945/ajcn.111.032268

Huffman, 2011, Essential fats: how do they affect growth and development of infants and young children in developing countries? A literature review, Matern Child Nutr., 7, 44, 10.1111/j.1740-8709.2011.00356.x

McGrath, 2006, Effect of maternal multivitamin supplementation on the mental and psychomotor development of children who are born to HIV-1-infected mothers in Tanzania, Pediatrics., 117, e216, 10.1542/peds.2004-1668

Faber, 2005, Effect of a fortified maize-meal porridge on anemia, micronutrient status, and motor development of infants, Am J Clin Nutr., 82, 1032, 10.1093/ajcn/82.5.1032

Aburto, 2010, The effect of nutritional supplementation on physical activity and exploratory behavior of Mexican infants aged 8-12 months, Eur J Clin Nutr., 64, 644, 10.1038/ejcn.2010.52

Delange, 1999, Risks of iodine-induced hyperthyroidism after correction of iodine deficiency by iodized salt, Thyroid., 9, 545, 10.1089/thy.1999.9.545

Dewey, 2008, Systematic review of the efficacy and effectiveness of complementary feeding interventions in developing countries, Matern Child Nutr., 4, 24, 10.1111/j.1740-8709.2007.00124.x