Nrf2 deficiency in aged mice exacerbates cellular senescence promoting cerebrovascular inflammation

Gábor Fülöp1, Tamás Kiss1, Stefano Tarantini2, Priya Balasubramanian3, Andriy Yabluchanskiy2, Eszter Farkas4, Ferenc Bari4, Zoltán Ungvári5, Anna Csiszár4
1Vascular Cognitive Impairment and Neurodegeneration Program, Reynolds Oklahoma Center on Aging/Department of Geriatric Medicine, University of Oklahoma Health Sciences Center, Oklahoma City, OK, USA
2Translational Geroscience Laboratory, Department of Geriatric Medicine, University of Oklahoma Health Sciences Center, Oklahoma City, USA
3Vascular Cognitive Impairment and Neurodegeneration Program, Reynolds Oklahoma Center on Aging, Department of Geriatric Medicine, University of Oklahoma Health Sciences Center, Oklahoma City, USA
4Department of Medical Physics and Informatics, University of Szeged, Szeged, Hungary
5Translational Geroscience Laboratory, Department of Geriatric Medicine, University of Oklahoma Health Sciences Center, Oklahoma City, OK, USA

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