Non‐infectious hyperthermia in acute brain injury patients: Relationships to mortality, blood pressure, intracranial pressure and cerebral perfusion pressure

International Journal of Nursing Practice - Tập 18 Số 3 - Trang 295-302 - 2012
Hyun Soo Oh1, Hye-Sun Jeong2, WhaSook Seo1
1Professor, Department of Nursing, Inha University, Incheon, Korea
2Assistant professor, Department of Nursing, Cheongju University, Cheongju, Chungbuk, Korea

Tóm tắt

Oh HS, Jeong HS, Seo WS. International Journal of Nursing Practice 2012; 18: 295–302Non‐infectious hyperthermia in acute brain injury patients: Relationships to mortality, blood pressure, intracranial pressure and cerebral perfusion pressureThe present study was conducted to investigate the frequency of hyperthermia during the first 72 h after acute brain injury, and to compare subjects that developed hyperthermia with those that did not with respect to blood pressure, intracranial pressure (ICP), cerebral perfusion pressure (CPP), Glasgow Coma Scale (GCS) score and mortality. This study was conducted by performing a retrospective medical record review of 126 brain injury patients admitted to the neurological intensive care unit of a university hospital located in Incheon, South Korea. Our results showed that 25.4% of the subjects had hyperthermia for at least 1 day during the first 3 days of hospitalization. Hyperthermic subjects demonstrated higher mortality and ICP, and lower CPP and GCS scores than non‐hyperthermic subjects, indicating a reduced cerebral blood flow. The findings may provide a possible explanation for poor clinical outcome and offer justification for the careful monitoring of body temperature in patients with acute brain injury.

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Tài liệu tham khảo

Broessner G, 2010, Prophylactic, endovascularly based, long‐term normothermia in ICU patients with severe cerebrovascular disease, Stroke, 21, e657

10.1001/archneur.61.3.321

10.1161/01.STR.29.12.2455

10.1136/jnnp.71.4.448

10.1056/NEJM200102223440803

10.3171/jns.1999.91.2.0185

10.1007/s00134-002-1513-1

10.1097/TA.0b013e318157dbec

10.1179/174313208X319125

10.1136/jnnp.2006.112730

10.1097/ANA.0b013e31815f528c

10.1016/S0025-6196(11)64885-4

10.1212/WNL.54.2.354

10.1212/WNL.56.10.1299