Neuropeptide W in the rat pancreas: Potentiation of glucose-induced insulin release and Ca2+ influx through L-type Ca2+ channels in β-cells and localization in islets

Shimomura, 2002, Identification of neuropeptide W as the endogenous ligand for orphan G-protein-coupled receptors GPR7 and GPR8, J Biol Chem, 277, 35826, 10.1074/jbc.M205337200 Lee, 1999, Two related G protein-coupled receptors. The distribution of GPR7 in rat brain and the absence of GPR8 in rodents, Mol Brain Res, 71, 96, 10.1016/S0169-328X(99)00171-0 Fujii, 2002, Identification of a neuropeptide modified with bromine as an endogenous ligand for GPR7, J Biol Chem, 277, 34010, 10.1074/jbc.M205883200 O 'Dowd, 1995, The cloning and chromosomal mapping of two novel human opioid-somatostatin-like receptor genes, GPR7 and GPR8, expressed in discrete areas of the brain, Genomics, 28, 84, 10.1006/geno.1995.1109 Brezillon, 2003, Identification of natural ligands for the orphan G protein-coupled receptors GPR7 and GPR8, J Biol Chem, 278, 776, 10.1074/jbc.M206396200 Dun, 2003, Neuropeptide W immunoreactivity in the hypothalamus and pituitary of the rat, Neurosci Lett, 349, 71, 10.1016/S0304-3940(03)00804-8 Ishii, 2003, Targeted disruption of GPR7, the endogenous receptor for neuropeptides B and W, leads to metabolic defects and adult-onset obesity, Proc Natl Acad Sci U S A, 100, 10540, 10.1073/pnas.1334189100 Tanaka, 2003, Characterization of a family of endogenous neuropeptide ligands for the G protein-coupled receptors GPR7 and GPR8, Proc Natl Acad Sci U S A, 100, 6251, 10.1073/pnas.0837789100 Baker, 2003, Neuropeptide W acts in brain to control prolactin, corticosterone, and growth hormone release, Endocrinology, 144, 2816, 10.1210/en.2002-0161 Mondal, 2003, A role for neuropeptide W in the regulation of feeding behavior, Endocrinology, 144, 4729, 10.1210/en.2003-0536 Samson, 2004, Central neuropeptide B administration activates stress hormone secretion and stimulates feeding in male rats, J Neuroendocrinol, 16, 842, 10.1111/j.1365-2826.2004.01239.x Levine, 2005, Injection of neuropeptide W into paraventricular nucleus of hypothalamus increases food intake, Am J Physiol, 288, R1727 Wollheim, 1981, Regulation of insulin release by calcium, Physiol Rev, 61, 914, 10.1152/physrev.1981.61.4.914 Yada, 1994, Pituitary adenylate cyclase activating polypeptide is an extraordinarily potent intra-pancreatic regulator of insulin secretion from islet β-cells, J Biol Chem, 269, 1290, 10.1016/S0021-9258(17)42256-3 Dezaki, 2004, Endogenous ghrelin in pancreatic islets restricts insulin release by attenuating Ca2+ signaling in β-cells: implication in the glycemic control in rodents, Diabetes, 53, 3142, 10.2337/diabetes.53.12.3142 Dezaki, 2006, Blockade of pancreatic islet-derived ghrelin enhances insulin secretion to prevent high-fat diet-induced glucose intolerance, Diabetes, 55, 3486, 10.2337/db06-0878 Yada, 1997, Pituitary adenylate cyclase-activating polypeptide (PACAP) is an islet substance serving as an intra-islet amplifier of glucose-induced insulin secretion in rats, J Physiol, 505, 319, 10.1111/j.1469-7793.1997.319bb.x Yada, 1993, Glucagon-like peptide-1-(7-36)amide and a rise in cyclic adenosine 3′,5′-monophosphate increase cytosolic free Ca2+ in rat pancreatic β-cells by enhancing Ca2+ channel activity, Endocrinology, 133, 1685, 10.1210/endo.133.4.8404610 Gromada, 2004, Glucagon-like peptide-1: regulation of insulin secretion and therapeutic potential, Basic Clin Pharmacol Toxicol, 95, 252, 10.1111/j.1742-7843.2004.t01-1-pto950502.x Henquin, 2003, Hierarchy of the β-cell signals controlling insulin secretion, Eur J Clin Invest, 33, 742, 10.1046/j.1365-2362.2003.01207.x Ashcroft, 2000, The β-cell KATP channel, J Membr Biol, 176, 187 Mondal, 2006, Neuropeptide W is present in antral G cells of rat, mouse, and human stomach, J Endocrinol, 188, 49, 10.1677/joe.1.06195 Hochol, 2006, Expression of neuropeptides B and W and their receptors in endocrine glands of the rat, Int J Mol Med, 18, 1101 Sharp, 1996, Mechanisms of inhibition of insulin release, Am J Physiol, 271, C1781, 10.1152/ajpcell.1996.271.6.C1781 Mazzocchi, 2005, G protein receptors 7 and 8 are expressed in human adrenocortical cells, and their endogenous ligands neuropeptides B and W enhance cortisol secretion by activating adenylate cyclase- and phospholipase C-dependent signaling cascades, J Clin Endocrinol Metab, 90, 3466, 10.1210/jc.2004-2132 Prentki, 1987, Ca2+, cAMP, and phospholipid-derived messengers in coupling mechanisms of insulin secretion, Physiol Rev, 67, 1185, 10.1152/physrev.1987.67.4.1185