Neuronal Oscillations in Cortical Networks

American Association for the Advancement of Science (AAAS) - Tập 304 Số 5679 - Trang 1926-1929 - 2004
György Buzsáki1,2, Andreas Draguhn1,2
1Center for Molecular and Behavioral Neuroscience, Rutgers, The State University of New Jersey, Newark, NJ 07102 USA
2Institut für Physiologie und Pathophysiologie, University of Heidelberg, INF 326, 69120 Heidelberg, Germany.

Tóm tắt

Clocks tick, bridges and skyscrapers vibrate, neuronal networks oscillate. Are neuronal oscillations an inevitable by-product, similar to bridge vibrations, or an essential part of the brain's design? Mammalian cortical neurons form behavior-dependent oscillating networks of various sizes, which span five orders of magnitude in frequency. These oscillations are phylogenetically preserved, suggesting that they are functionally relevant. Recent findings indicate that network oscillations bias input selection, temporally link neurons into assemblies, and facilitate synaptic plasticity, mechanisms that cooperatively support temporal representation and long-term consolidation of information.

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We apologize to those whose work was not cited because of space constraints. We thank C. Brühl D. L. Buhl I. Creese J. Csicsvari W. J. Freeman K. D. Harris D. A. Henze N. Kopell N. Maier A. Sirota X-J. Wang and M. Zugaro for discussions. Supported by the National Institute of Mental Health and the National Institute of Neurological Disorders and Stroke.