Neurogenesis in the adult human hippocampus

Altman, J. &. Das, G.D. Autoradiographic and histological evidence of postnatal hippocampal neurogenesis in rats. >J. Comp. Neurol. 124, 319–335 ( 1965).

Altman, J. & Das, G.D. Postnatal neurogenesis in the guinea-pig. Nature 214, 1098–1101 (1967).

Caviness, V.S. Time of neuron origin in the hippocampus and dentate gyrus of normal and reeler mutant mice: an autoradiographic analysis. J. Comp. Neurol. 151, 113–120 (1973).

Gueneau, G., Privat, A., Drouet, J. & Court, L. Subgranular zone of the dentate gyrus of young rabbits as a secondary matrix. A high-resolution autoradiographic study. Dev. Neurosci. 5, 345–358 (1982).

Kuhn, H.G., Dickinson-Anson, H. & Gage, F.H. Neurogenesis in the dentate gyrus of the adult rat: Age-related decrease of neuronal progenitor proliferation. J. Neurosci. 16, 2027–2033 ( 1996).

Gould, E., Tanapat, P., McEwen, B.S., Flugge, G. & Fuchs, E. Proliferation of granule cell precursors in the dentate gyrus of adult monkeys is diminished by stress. Proc. Natl. Acad. Sci. USA 95, 3168– 3171 (1998).

Kaplan, M.S. & Bell, D.H. Mitotic neuroblasts in the 9-day-old and 11-month-old rodent hippocampus. J. Neurosci. 4 , 1429–1441 (1984).

Kaplan, M.S. & Hinds, J.W. Neurogenesis in the adult rat: electron microscopic analysis of light radioautographs. Science 197, 1092–1094 (1977).

Stanfield, B.B. & Trice, J.E. Evidence that granule cells generated in the dentate gyrus of adult rats extend axonal projections. Exp. Brain Res. 72, 399– 406 (1988).

Cameron, H.A., Woolley, C.S., McEwen, B.S. & Gould, E. Differentiation of newly born neurons and glia in the dentate gyrus of the adult rat. Neuroscience 56, 337– 344 (1993).

Dolbeare, F. Bromodeoxyuridine: a diagnostic tool in biology and medicine, Part I: Historical perspectives, histochemical methods and cell kinetics. Histochem. J. 27, 339–369 ( 1995).

Kempermann, G., Kuhn, H.G. & Gage, F.H. Genetic influence on neurogenesis in the dentate gyrus of adult mice. Proc. Natl. Acad. Sci. USA 94, 10409–10414 (1997).

del Rio, J.A. & Soriano, E. Immunocytochemical detection of 5'-bromodeoxyuridine incorporation in the central nervous system of the mouse. Dev. Brain Res. 49, 311– 317 (1989).

Gundersen, H.J. et al. The new stereological tools: disector, fractionator, nucleator and point sampled intercepts and their use in pathological research and diagnosis. APMIS 96, 857–881 (1988).

West, M.J. Regionally specific loss of neurons in the aging human hippocampus. Neurobiol. Aging 14, 287–293 (1993).

Coggeshall, R.E. & Lekan, H.A. Methods for determining numbers of cells and synapses: a case for more uniform standards of review. J. Comp. Neurol. 364, 6– 15 (1996).

Kempermann, G., Kuhn, H.G. & Gage, F.H. More hippocampal neurons in adult mice living in an enriched environmen Nature 386, 493– 495 (1997).

Mullen, R.J., Buck, C.R. & Smith, A.M. NeuN, a neuronal specific nuclear protein in vertebrates. Development 116, 201–211 (1992).

Wolf, H.K. et al. NeuN: A useful neuronal marker for diagnostic histopathology. J. Histochem. Cytochem. 44, 1167– 1171 (1996).

Sloviter, R.S. Calcium-binding protein (calbindin-D28k) and parvalbumin immunocytochemistry: localization in the rat hippocampus with specific reference to the selective vulnerability of hippocampal neurons to seizure activity. J. Comp. Neurol. 280, 183–196 ( 1989).

Schmechel, D., Marango, P.J., Zis, A.P., Brightman, M. & Goodwin, F.K. Brain enolases as specific markers of neuronal and glial cells. Science 199, 313– 315 (1978).

Kirschenbaum, B. et al. In vitro neuronal production and differentiation by precursor cells derived from the adult human forebrain. Cereb. Cortex 4, 576–589 ( 1994).

Rakic, P. Limits of neurogenesis in primates. Science 227, 1054–1056 (1985).

Eckenhoff M.F. & Rakic, P. Nature and fate of proliferative cells in the hippocampal dentate gyrus during the life span of the rhesus monkey. J. Neurosci. 8, 2729 –2747 (1988).

Kempermann, G., Kuhn, H.G. & Gage, F.H. Experience-induced neurogenesis in the senescent dentate gyrus. J. Neurosci. 18, 3206– 3212 (1998).

Gage, F.H. et al. Survival and differentiation of adult neuronal progenitor cells transplanted to the adult brain. Proc. Natl. Acad. Sci. USA 92, 11879–11883 ( 1995).

Suhonen, J.O., Peterson, D.A., Ray, J. & Gage, F.H. Differentiation of adult hippocampus-derived progenitors into olfactory neurons in vivo. Nature 383, 624–627 ( 1996).