Natural killer cell immunotypes related to COVID-19 disease severity

Science immunology - Tập 5 Số 50 - 2020
Christopher Maucourant1, Iva Filipovic1, Andrea Ponzetta1, Soo Aleman2,3, Martin Cornillet1, Laura M. Palma Medina1, Benedikt Strunz1, Antonio Lentini4, Björn Reinius4, Demi Brownlie1, Angélica Cuapio1, Eivind Heggernes Ask5,6, Ryan M. Hull7, Alvaro Haroun-Izquierdo1, Marie Schaffer1, Jonas Klingström1, Elin Folkesson2,8, Marcus Buggert1, Johan K. Sandberg1, Lars I. Eriksson9,10, Olav Rooyackers11,10, Hans‐Gustaf Ljunggren1, Karl‐Johan Malmberg1,5,6, Jakob Michaëlsson1, Nicole Marquardt1, Quirin Hammer1, Kristoffer Strålin2,3, Niklas K. Björkström1
1Center for Infectious Medicine, Department of Medicine Huddinge, Karolinska Institutet, Karolinska University Hospital, Stockholm, Sweden
2Department of Infectious Diseases, Karolinska University Hospital, Stockholm, Sweden
3Division of Infectious Diseases and Dermatology, Department of Medicine Huddinge, Karolinska Institutet, Stockholm, Sweden.
4Department of Medical Biochemistry and Biophysics, Karolinska Institutet, Stockholm, Sweden
5Department of Cancer Immunology, Institute for Cancer Research, Oslo University Hospital, Oslo, Norway
6K.G. Jebsen Centre for Cancer Immunotherapy, Institute of Clinical Medicine, University of Oslo, Oslo, Norway.
7SciLifeLab, Department of Microbiology, Tumor and Cell Biology, Karolinska Institutet, Stockholm, Sweden
8Division of Infectious Diseases, Department of Medicine Solna Karolinska Institutet, Stockholm, Sweden
9Department of Physiology and Pharmacology, Section for Anesthesiology and Intensive Care, Karolinska Institutet, Stockholm, Sweden
10Function Perioperative Medicine and Intensive Care, Karolinska University Hospital, Stockholm, Sweden
11Department of Clinical Science, Intervention, and Technology (CLINTEC), Division for Anesthesiology and Intensive Care, Karolinska Institutet, Stockholm, Sweden.

Tóm tắt

The NK cell activation landscape in acute SARS-CoV-2 infection is associated with COVID-19 disease severity.

Từ khóa


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Science immunology

Tập 5 Số 50

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