Natural FCoV infection: Cats with FIP exhibit significantly higher viral loads than healthy infected cats

Journal of Feline Medicine and Surgery - Tập 8 - Trang 69-72 - 2006
Anja Kipar1,2, Keith Baptiste2, Andreas Barth1, Manfred Reinacher1
1Institut für Veterinär-Pathologie, Justus-Liebig-Universität Giessen, Giessen, Germany
2Department of Veterinary Pathology, Faculty of Veterinary Science, University of Liverpool, Crown Street, Liverpool L69 7ZJ, UK

Tóm tắt

Natural feline coronavirus (FCoV) infection has been shown to not only induce intestinal infection with viral shedding, but also systemic infection which either remains without clinical signs or leads to feline infectious peritonitis (FIP). As systemic infection is not the key event in the development of FIP, the question arises as to whether a potential difference in viral load might be of importance. Therefore, the purpose of this study was to quantitatively assess feline coronavirus (FCoV) RNA loads in haemolymphatic tissues of healthy, long-term FCoV-infected cats and cats with FIP. In cats that died from FIP, viral loads were significantly higher, indicating a higher rate of viral replication or a reduced capacity for viral clearance in cats developing and/or suffering from FIP.

Tài liệu tham khảo

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Thông tin xuất bản

Journal of Feline Medicine and Surgery

Tập 8

69-72

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