Nasopharyngeal Flora in the First Three Years of Life in Normal and Otitis-Prone Children

Annals of Otology, Rhinology and Laryngology - Tập 100 Số 8 - Trang 612-615 - 1991
Howard Faden1, Linda Brodsky1, Mary Jane Waz1, John Stanievich1, Joel M. Bernstein1, Pearay L. Ogra1
1Buffalo, New York

Tóm tắt

Nasopharyngeal carriage of the three major middle ear pathogens ( Streptococcus pneumoniae, nontypeable Hemophilus influenzae, and Moraxella catarrhalis) was evaluated prospectively in a group of 110 children followed up for the first 3 years of life. The findings suggested that nasopharyngeal carriage of middle ear pathogens increases significantly during respiratory illness among the general population of young children; however, otitis-prone children demonstrated a tendency to carry nontypeable H influenzae at an unusually high rate even during health. This propensity to carry nontypeable H influenzae might explain why nontypeable H influenzae is a major cause of recurrent or chronic otitis media.

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Tài liệu tham khảo

10.1001/archpedi.1945.02020160008002

Ingvarsson L, Lundgren K, Ursing J. The bacterial flora in the nasopharynx in healthy children. Acta Otolaryngol [Suppl] (Stockh) 1982(suppl 386): 94–6.

10.1056/NEJM198207083070203

10.1093/infdis/132.1.55

10.1016/S0022-3476(75)80120-X

10.1093/oxfordjournals.aje.a114169

10.1017/S0950268800067327

10.1093/clinids/9.1.16

10.1128/jcm.13.6.1017-1022.1981

Lennette EH, 1985, Manual of clinical microbiology, 4

10.3109/00016488409107572

10.1093/clinids/8.4.533

Faden H, 1990, Pediatr Infect Dis J, 9, 623

10.3109/00016488809119455

Chonmaitree T, 1987, Immunology of the ear, 231

10.3109/00016488409130971