Naringin Cải Thiện Hoạt Động CaMKII và Tăng Cường Trí Nhớ Dài Hạn Trong Mô Hình Chuột Bệnh Alzheimer
Tóm tắt
Từ khóa
#Amyloid-β #trí nhớ #Alzheimer's disease #naringin #CaMKII #tính dẻo synap #phosphoryl hóa #chuột chuyển gen #chức năng nhận thứcTài liệu tham khảo
Stokin, 2005, Axonopathy and transport deficits early in the pathogenesis of Alzheimer’s disease, Science, 307, 1282, 10.1126/science.1105681
Ballatore, 2007, Tau-mediated neurodegeneration in Alzheimer’s disease and related disorders, Nat. Rev. Neurosci, 8, 663, 10.1038/nrn2194
Auld, 2002, Alzheimer’s disease and the basal forebrain cholinergic system: Relations to beta-amyloid peptides, cognition, and treatment strategies, Prog. Neurobiol, 68, 209, 10.1016/S0301-0082(02)00079-5
Green, 2010, Memantine improves cognition and reduces Alzheimer’s-like neuropathology in transgenic mice, Am. J. Pathol, 176, 870, 10.2353/ajpath.2010.090452
Selkoe, 2008, Soluble oligomers of the amyloid beta-protein impair synaptic plasticity and behavior, Behav. Brain Res, 192, 106, 10.1016/j.bbr.2008.02.016
Shankar, 2009, Alzheimer’s disease: Synaptic dysfunction and Abeta, Mol. Neurodegener, 4, 48, 10.1186/1750-1326-4-48
Chakroborty, 2012, Early presynaptic and postsynaptic calcium signaling abnormalities mask underlying synaptic depression in presymptomatic Alzheimer’s disease mice, J. Neurosci, 32, 8341, 10.1523/JNEUROSCI.0936-12.2012
Zeng, 2010, Neurotrophins enhance CaMKII activity and rescue amyloid-beta-induced deficits in hippocampal synaptic plasticity, J. Alzheimer’s Dis, 21, 823, 10.3233/JAD-2010-100264
Schroeter, 2002, MAPK signaling in neurodegeneration: Influences of flavonoids and of nitric oxide, Neurobiol. Aging, 23, 861, 10.1016/S0197-4580(02)00075-1
Pereira, 2007, Synthesis and characterization of a metal complex containing naringin and Cu, and its antioxidant, antimicrobial, antiinflammatory and tumor cell cytotoxicity, Molecules, 12, 1352, 10.3390/12071352
Cui, 2012, Effect of β-cyclodextrin complexation on solubility and enzymatic conversion of naringin, Int. J. Mol. Sci, 13, 14251, 10.3390/ijms131114251
Golechha, 2011, Naringin protects against kainic acid-induced status epilepticus in rats: Evidence for an antioxidant, anti-inflammatory and neuroprotective intervention, Biol. Pharm. Bull, 34, 360, 10.1248/bpb.34.360
Kumar, 2010, Protective effect of hesperidin and naringin against 3-nitropropionic acid induced Huntington’s like symptoms in rats: Possible role of nitric oxide, Behav. Brain Res, 206, 38, 10.1016/j.bbr.2009.08.028
Kumar, 2010, Protective effect of naringin, a Citrus flavonoid, against colchicine-induced cognitive dysfunction and oxidative damage in rats, J. Med. Food, 13, 976, 10.1089/jmf.2009.1251
Kumar, 2010, Naringin alleviates cognitive impairment, mitochondrial dysfunction and oxidative stress induced by D-galactose in mice, Food Chem. Toxicol, 48, 626, 10.1016/j.fct.2009.11.043
Wang, 2012, Long-term naringin consumption reverses a glucose uptake defect and improves cognitive deficits in a mouse model of Alzheimer’s disease, Pharm. Biochem. Behav, 102, 13, 10.1016/j.pbb.2012.03.013
Insausti, 1995, The human entorhinal cortex: A cytoarchitectonic analysis, J. Comp. Neurol, 355, 171, 10.1002/cne.903550203
Shankar, 2008, Amyloid-beta protein dimers isolated directly from Alzheimer’s brains impair synaptic plasticity and memory, Nat. Med, 14, 837, 10.1038/nm1782
Amada, 2005, Reduction of NR1 and phosphorylated Ca2+/calmodulin-dependent protein kinase II levels in Alzheimer’s disease, Neuroreport, 16, 1809, 10.1097/01.wnr.0000185015.44563.5d
Lisman, 2012, Mechanisms of CaMKII action in long-term potentiation, Nat. Rev. Neurosci, 13, 169, 10.1038/nrn3192
Strack, 1997, Translocation of autophosphorylated calcium/calmodulin-dependent protein kinase II to the postsynaptic density, J. Biol. Chem, 272, 13467, 10.1074/jbc.272.21.13467
Benfenati, 1992, Synaptic vesicle-associated Ca2+/calmodulin-dependent protein kinase II is a binding protein for synapsin I, Nature, 359, 417, 10.1038/359417a0
Derkach, 1999, Ca2+/calmodulin-kinase II enhances channel conductance of alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionate type glutamate receptors, Proc. Natl. Acad. Sci. USA, 96, 3269, 10.1073/pnas.96.6.3269
Liu, 2010, Amyloid-beta decreases cell-surface AMPA receptors by increasing intracellular calcium and phosphorylation of GluR2, J. Alzheimer’s Dis, 21, 655, 10.3233/JAD-2010-091654
Espana, 2011, Soluble oligomers of amyloid-beta peptide disrupt membrane trafficking of alpha-amino-3-hydroxy-5-methylisoxazole-4-propionic acid receptor contributing to early synapse dysfunction, J. Biol. Chem, 286, 27311, 10.1074/jbc.M111.227504
Lanz, 2003, Dendritic spine loss in the hippocampus of young PDAPP and Tg2576 mice and its prevention by the ApoE2 genotype, Neurobiol. Dis, 13, 246, 10.1016/S0969-9961(03)00079-2
Hayashi, 2000, Driving AMPA receptors into synapses by LTP andCaMKII: Requirement for GluR1 and PDZ domain interaction, Science, 287, 2262, 10.1126/science.287.5461.2262
Jourdain, 2003, Calcium/calmodulin-dependent protein kinase II contributes to activity-dependent filopodia growth and spine formation, J. Neurosci, 23, 10645, 10.1523/JNEUROSCI.23-33-10645.2003
Wayman, 2008, Calmodulin-kinases: Modulators of neuronal development and plasticity, Neuron, 59, 914, 10.1016/j.neuron.2008.08.021
Zhu, 2007, Activation of glycogen synthase kinase-3 inhibits long-term potentiation with synapse-associated impairments, J. Neurosci, 27, 12211, 10.1523/JNEUROSCI.3321-07.2007
Song, 2010, Inhibitory phosphorylation of GSK-3 by CaMKII couples depolarization to neuronal survival, J. Biol. Chem., 285, 41122, 10.1074/jbc.M110.130351
Sudto, 2009, An efficient method for the large scale isolation of naringin from pomelo (Citrus grandis) peel, Int. J. Food Sci. Tech, 44, 1737, 10.1111/j.1365-2621.2009.01989.x
Nihal, 2008, Dose translation from animal to human studies revisited, FASEB J, 22, 659, 10.1096/fj.07-9574LSF