NETs Are a Source of Citrullinated Autoantigens and Stimulate Inflammatory Responses in Rheumatoid Arthritis

Ritika Khandpur1, Carmelo Carmona‐Rivera1, Anuradha Vivekanandan‐Giri2, Alison M. Gizinski1, Srilakshmi Yalavarthi1, Jason S. Knight1, Sean C. Friday1, Sam Li1, Rajiv M. Patel3, Venkataraman Subramanian4, Paul R. Thompson4, Pojen Chen5, David A. Fox1, Subramaniam Pennathur2, Mariana J. Kaplan1
1Division of Rheumatology, Department of Internal Medicine, University of Michigan, Ann Arbor, MI 48109, USA
2Division of Nephrology, Department of Internal Medicine, University of Michigan, Ann Arbor, MI 48109, USA
3Department of Pathology; University of Michigan; Ann Arbor MI 48109 USA
4Department of Chemistry, Scripps Florida, Jupiter, FL 33458, USA.
5Division of Rheumatology, University of California, Los Angeles, Los Angeles, CA 90095, USA.

Tóm tắt

Neutrophil NETs may contribute to pathogenesis of rheumatoid arthritis.

Từ khóa


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