NEW INSIGHTS INTO THE REGULATION AND FUNCTIONAL SIGNIFICANCE OF LYSINE METABOLISM IN PLANTS

Annual Review of Plant Biology - Tập 53 Số 1 - Trang 27-43 - 2002
Gad Galili1
1Department of Plant Sciences, The Weizmann Institute of Science, Rehovot 76100, Israel

Tóm tắt

▪ Abstract  Lysine is one of the most limiting essential amino acids in vegetative foods consumed by humans and livestock. In addition to serving as a building block of proteins, lysine is also a precursor for glutamate, an important signaling amino acid that regulates plant growth and responses to the environment. Recent genetic, molecular, and biochemical evidence suggests that lysine synthesis and catabolism are regulated by novel concerted mechanisms. These include intracellular compartmentalization of enzymes and metabolites, complex transcriptional and posttranscriptional controls of genes encoding enzymes in lysine metabolism during plant growth and development, as well as interactions between different metabolic fluxes. The recent advances in our understanding of the regulation of lysine metabolism in plants may also prove valuable for future production of high-lysine crops.

Từ khóa


Tài liệu tham khảo

10.1128/MCB.17.10.5968

10.1016/S1360-1385(00)01688-5

10.1002/j.1460-2075.1996.tb00662.x

10.1007/BF00020213

10.1104/pp.124.4.1615

10.1080/07352688309382171

10.1007/BF00020202

Burbulis IE, 1996, SAAS Bull. Biochem. Biotechnol., 9, 29

10.1073/pnas.96.22.12929

10.1105/tpc.9.1.97

Cohen GN, Saint-Girons I. 1987. Biosynthesis of threonine, lysine and methionine. InEscherichia coli and Salmonella typhimurium: Cellular and Molecular Biology, ed. FC Neidhardt, pp. 429–44. Washington, DC: Am. Soc. Microbiol.

10.1016/S0014-5793(00)02303-6

10.1046/j.1365-3040.1999.00471.x

10.1104/pp.124.4.1511

10.1023/A:1005808923191

10.1038/nbt0695-577

Farfan MJ, 1999, Appl. Environ. Microbiol., 65, 110, 10.1128/AEM.65.1.110-116.1999

10.1104/pp.99.4.1285

10.1105/tpc.7.7.899

10.1016/S1369-5266(00)00170-9

Jacobs M, Vauterin M, De Waele E, Craciun A. 2001. Manipulating plant biochemical pathways for improved nutritional quality. InPlant Biotechnology and Transgenic Plants. New York: Marcel Dekker

10.1105/tpc.7.11.1963

10.1073/pnas.91.7.2577

10.1046/j.1432-1327.1998.2530720.x

10.1105/tpc.11.10.1981

10.1093/pcp/pce008

10.1073/pnas.97.16.8849

Krapp A, 1993, Plant Physiol., 99, 627

10.1105/tpc.7.7.887

10.1038/24066

10.1046/j.1365-313x.1998.00302.x

Markovitz PJ, 1984, J. Biol. Chem., 259, 11643, 10.1016/S0021-9258(20)71252-4

10.1126/science.285.5426.372

10.1038/32317

10.1046/j.1365-313x.1997.12061453.x

10.1016/S0981-9428(00)00777-4

10.1104/pp.106.4.1303

10.1007/BF00252303

10.1016/S1369-5266(99)80026-0

10.1128/jb.175.3.785-794.1993

10.1128/jb.175.4.959-965.1993

10.1042/0264-6021:3440555

10.1016/S0014-5793(00)02401-7

10.1007/BF00027077

Rafalski JA, 1988, J. Biol. Chem., 263, 2146, 10.1016/S0021-9258(18)69183-5

Rao S, 1999, Biochem. Mol. Biol. Int., 47, 347

Rao VV, 1992, Comp. Biochem. Physiol., 103, 221, 10.1016/0300-9629(92)90266-S

10.1105/tpc.6.5.737

10.1046/j.1365-313x.2000.00884.x

10.1111/j.1365-313X.1992.00203.x

10.1007/BF00021531

Shotwell MA, Larkins BA. 1989. The biochemistry and molecular biology of seed storage proteins. InThe Biochemistry of Plants, ed. A Marcus, pp. 297–345. San Diego, CA: Academic

10.1146/annurev.pp.36.060185.001001

10.1105/tpc.9.8.1305

10.1046/j.1365-313x.2000.00770.x

Thorne JH, Giaquinata RT. 1984. Pathways and mechanisms associated with carbohydrate translocation in plants. InStorage Carbohydrates in Vascular Plants: Distribution,Physiology and Metabolism, ed. DH Lewis, pp. 75–96. Cambridge, UK: Cambridge Univ. Press

10.1023/A:1006132428623

10.1021/ar000057q

10.1007/BF00199748

Woody NC, 1964, Am. J. Dis. Child., 108, 543

10.1104/pp.126.4.1539

10.1104/pp.116.3.1023

10.1104/pp.113.3.695