N-3 polyunsaturated fatty acids prevent the <scp>d</scp>-galactose-induced cognitive impairment by up-regulating the levels of 5-hydroxymethylcytosine in the mouse brain

Food and Function - Tập 13 Số 7 - Trang 4101-4113
Tianyu Zhang1, Lei Chen1, Xiaofei Guo1, Shan Li1, Xin He1, Shengjie Pei1, Duo Li1
1Institute of Nutrition and Health, Qingdao University, Qingdao, China

Tóm tắt

Peony seed oil and fish oil increased the docosahexaenoic acid content, which activated the TET activity, led to up-regulation of the 5hmc level, resulted in inhibition of neuronal apoptosis, and then improved the cognitive function in d-gal-induced mice.

Từ khóa


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