Mushroom bodies are not required for courtship behavior by normal and sexually mosaic <i>Drosophila</i>

Wiley - Tập 52 Số 4 - Trang 302-311 - 2002
Asami Kido1, Kei Ito
1National Institute for Basic Biology, Myodaiji Okazaki, Aichi 444-8585, Japan

Tóm tắt

AbstractTo elucidate the effect of feminization of male Drosophila brain cells on courtship control, we performed a large scale screening of expression drivers that can suppress male‐specific behavior with transformer gene expression. Two drivers caused essentially total courtship suppression. The expression pattern of these drivers did not show any correlation with the mushroom bodies or the antennal lobes, the regions that have been suggested to play important roles in courtship. Ablation of mushroom bodies using hydroxyurea treatment did not affect this courtship suppression. The ablation did not change either wild‐type heterosexual behavior or bisexual behavior caused by transformer expression driven by the same drivers used in the previous studies to suggest the involvement of the mushroom bodies in courtship. Our results show that feminization of different nonoverlapping cells in other parts of the protocerebrum was sufficient to cause the same bisexual or suppressed‐courtship phenotype. Thus, contrary to previous assumptions, the mushroom bodies are not required for the control of courtship. Present evidence supports its mediation by other distributed protocerebral regions. © 2002 Wiley Periodicals, Inc. J Neurobiol 52: 302–311, 2002

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Tài liệu tham khảo

10.1016/S0960-9822(07)00491-5

10.1523/JNEUROSCI.18-11-04335.1998

de Belle JS, 1994, Associative odor learning in Drosophila abolished by chemical ablation of mushroom bodies, Science, 263, 692, 10.1126/science.8303280

10.3109/01677069809108559

10.1126/science.276.5318.1555

10.1126/science.7846534

10.1093/genetics/154.2.725

10.1093/genetics/92.2.437

10.1126/science.8209251

10.1073/pnas.011314898

10.3109/01677068509100140

10.1038/240527a0

10.1242/dev.124.4.761

Ito K, 1998, The organization of extrinsic neurons and their implications regarding the functional roles of the mushroom bodies in Drosophila melanogaster Meigen, Learn Mem, 5, 52, 10.1101/lm.5.1.52

10.1007/BF02179499

Koana T, 1978, Isolation and characterization of flightless mutants in Drosophila melanogaster, J Embryol Exp Morphol, 45, 123

10.1242/dev.129.2.409

10.1002/1097-4695(20000615)43:4<404::AID-NEU8>3.0.CO;2-D

10.1016/0896-6273(94)90022-1

Martin JR, 1998, Mushroom bodies suppress locomotor activity in Drosophila melanogaster, Learn Mem, 5, 179, 10.1101/lm.5.1.179

10.1016/0896-6273(95)90064-0

10.1006/dbio.1994.1034

10.1002/bies.1083

10.1046/j.1440-169X.1996.00012.x

10.1007/BF00305372

10.1002/(SICI)1097-4695(199705)32:5<443::AID-NEU1>3.0.CO;2-5

10.1007/978-3-642-66179-2

10.1093/genetics/147.3.1107

Yoshihara M, 2000, Improved Gal4 screening kit for large‐scale generation of enhancer‐trap strains, DIS, 83, 199

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Wiley

Tập 52 Số 4

302-311

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