Movement‐related cortical potentials in writer's cramp

Annals of Neurology - Tập 38 Số 6 - Trang 862-868 - 1995
Günther Deuschl1, Camilo Toro2, Joseph Y. Matsumoto2, Mark Hallett3
1Human Motor Control Section, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD 20892-1428, USA
2Human Motor Control Section, Medical Neurology Branch, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD > > > > > >
3Human Motor Control Section, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Building 10, Room 5N226, 10 Center Drive MSC 1428, Bethesda, MD 20892–1428

Tóm tắt

AbstractMovement‐related cortical potentials in response to simple, self‐paced, brisk index finger abduction movements were recorded in patients with simple and complex writer's cramp and compared with those of age‐matched control subjects. Analysis of the movement‐related cortical potential waveforms showed that the Bereitschaftspotential, the peak of the negative slope, and the frontal peak of the motor potential did not differ in the two groups, except for the average amplitude of the early part of the negative‐slope peak, which was decreased in the patient group during the interval of 300 to 200 msec prior to electromyographic onset. This finding was restricted to the electrodes overlying the contralateral and midline central electrodes. Movement‐related cortical potentials from patients and control subjects could be equally accounted for by a four‐dipole source model with sources located in the contralateral and ipsilateral sensorimotor regions and the supplementary motor area. There was a trend for a reduction in the strength of the sensorimotor sources active during the premotor period in the patient group, but the difference did not reach a significant level for any individual source. No differences were found between the movement‐related cortical potentials elicited by movements of the affected and unaffected hand, or between those of patients with simple or complex hand cramps. This result suggests a deficiency of contralateral motor cortex activation just prior to the initiation of voluntary movements in patients with focal dystonia.

Từ khóa


Tài liệu tham khảo

10.1007/BF00336013

10.1016/0013-4694(80)90216-3

Tamas LB, 1985, Cortical potentials associated with movements: a review, Electroencephalogr Clin Neurophysiol, 2, 157

10.1097/00004691-199107010-00009

10.1016/0013-4694(93)90004-F

10.1016/0013-4694(90)90086-Y

Neshige R, 1988, Recording of the movement‐related potentials from scalp and cortex in man, Brain, 111, 719

10.1093/brain/115.4.1017

10.1016/0168-5597(93)90132-9

Oldfield RC, 1971, The assessment and analysis of handedness: the Edinburgh inventory, Neuropsychology, 9, 97, 10.1016/0028-3932(71)90067-4

10.1093/brain/105.3.461

10.1016/0013-4694(85)90042-2

10.1007/BF00248283

Lang W, 1984, Brain potentials related to voluntary hand tracking, motivation and attention, Hum Neurobiol, 3, 235

10.1093/brain/112.1.233

10.1136/jnnp.57.1.100

10.1093/brain/112.3.681

10.1212/WNL.39.1.85

10.1212/WNL.40.5.824

10.1016/0022-510X(92)90269-Q

10.1093/brain/108.3.593

10.1212/WNL.39.4.572

10.1016/0168-5597(92)90005-V

Toro C, 1993, Movement‐related EEG desynchronization in patients with hand cramps: evidence for cortical involvement in hand cramps, Neurology, 43, A379

10.1093/brain/113.3.691

10.1212/WNL.43.11.2252

Ceballos‐Baumann AO, 1994, Cerebral activation with performing and imaging movement in idiopathic torsion dystonia: a PET study, Neurology, 44, 839S

10.1017/S0317167100047909

10.1136/jnnp.48.8.782

10.1212/WNL.38.7.1005

Thông tin
Thông tin xuất bản

Annals of Neurology

Tập 38 Số 6

862-868

Thông tin tác giả