Molecular and developmental characterization of the heat shock cognate 4 gene of Drosophila melanogaster.

Molecular and Cellular Biology - Tập 10 Số 6 - Trang 3232-3238 - 1990
Lizabeth A. Perkins1,2,3, J S Doctor1,2,3, K Zhang1,2,3, L Stinson1,2,3, Norbert Perrimon1,2,3, E A Craig1,2,3
1Howard Hughes Medical Institute, Department of Genetics, Harvard Medical School, 25 Shattuck Street, Boston, Massachusetts 021151 and Department of Physiological Chemistry,
2McArdle Laboratory, University of Wiscon-sin, Madison, WI 53706. ' .
3University of Wisconsin, Madison, Wisconsin 537062

Tóm tắt

The Drosophila heat shock cognate gene 4 (hsc4), a member of the hsp70 gene family, encodes an abundant protein, hsc70, that is more similar to the constitutively expressed human protein than the Drosophila heat-inducible hsp70. Developmental expression revealed that hsc4 transcripts are enriched in cells active in endocytosis and those undergoing rapid growth and changes in shape.

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